Multiple cancer clusters

A woman s lifetime risk of breast cancer is approximately 1 in 8, Breast cancer clusters in families the risk of breast cancer doubles for a woman with one affected first-degree relative (e.g., mother, sister, or daughter). The risk increases further if there are multiple affected relatives or if the relatives developed early-onset breast cancer. 

The cancer clusters may be in the form of single cancers per cluster or of specific multiple cancers per cluster. 

Naval divers in Israel train in the Kishon River. Pollution in the Kishon River ranks among the highest in the world, reaching levels close to those in the Rhine, Alba, and Po rivers. Divers who have trained in these waters form a cancer cluster of multiple cancers that are not only far in excess of cancers in the general population, but also have very short induction periods. I24 The cancers found in the divers include... 

Cluster 1 Childhood Leukemia 468 Cluster 2 Prostate Cancer 468 Clusters 3-6 Testicular Cancer 469 Cluster 7 Brain Cancer Cluster—Electronic Workers 469 Cluster 8 Brain Cancer Cluster—Petrochemical Workers 470 Cluster 9 Brain Cancers in Offspring of Electronic Workers 470 Cluster 10 Kidney Cancer Cluster 471 Cluster 11 Colorectal Cancer Cluster 471 Cluster 12 Multiple Cancer Cluster 471 Cluster 13 Lung Cancer Cluster 472 Cluster 14 Childhood Leukemia 472 Cluster 15 Multiple Cancer Clusters 473 Cluster 16 Toxic Waste Disposal Site-Related Clusters 474... 

Proteomic Mapping and Clustering of Multiple Samples—Application to Ovarian Cancer Cell Lines... 

Fig. 9 Two alternative designs for a dendritic nanodevice cancer therapeutic. Configuration 1 is a therapeutic agent built around a single dendrimer molecule (70 A in diameter). Configuration 2 is a cluster reagent where multiple dendrimers are clustered together, each providing a different functional unit (approx. 200 A in diameter). The advantage to this latter approach is that functional units can be mixed and matched in a combinatory method to address almost any type of cancer. (From Ref., 2001 Kluwer Academic Publishers.)...

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