Cancer, breast prostate gland

HER-2/neu or ERB-B2 Codes for a growth factor receptor Breast, salivary gland, prostate, bladder and ovarian cancers... 

Pronounced changes of arylsulfohydrolases have been observed in many pathological states. Many diseases are associated with increased excretion of arylsulfohydrolases in urine. A 30-fold increase of arylsulfohydrolase activity is observed in myeloid leukemia. Rather substantial increases in sulfohydrolases are also noticed in diseases of the bladder, testes, and uterus and in cancer of the breast and the prostate gland (Dzialozynski and Gniot-Szulzycka, 1967 Posey and Morgan, 1977 Peltonen et al., 1981). 

In some cases, local irradiation of some tissues is produced by the use of radioactive nuclides inmlanted in the tissue by means of needles or small capsules. For example, needles of "Sr— Y, pellets of Au, etc., have been inqilanted in the pituitary gland (for acromegalia, Cushing s disease, and cancer), in the breast (for breast cancer), in the prostate, and in the nerves (to reduce pain). The local dose may be lOO s of Sv. Also, radioactively labeled tumor seeking compounds are used. 

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