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Calibration Bayesian

Fig. 8.11. The classifier development process. Clinical knowledge provides us with a set of classes for supervised classification (top, right). Large numbers of spectra from large sample numbers are reduced to a set of potentially useful features (top, left) or metrics. A modified Bayesian algorithm operates on the metrics to provide predictions that are compared to a gold standard. The end result of the training and validation process is an optimized algorithm, metric set, calibration and validation statistics, and sensitivity analysis of the data... Fig. 8.11. The classifier development process. Clinical knowledge provides us with a set of classes for supervised classification (top, right). Large numbers of spectra from large sample numbers are reduced to a set of potentially useful features (top, left) or metrics. A modified Bayesian algorithm operates on the metrics to provide predictions that are compared to a gold standard. The end result of the training and validation process is an optimized algorithm, metric set, calibration and validation statistics, and sensitivity analysis of the data...
Bayesian regularization 733 BDD 213 Beers e279 (Bio)composites 145 Biosensor calibration el73 Bioavailability 28, 47 Biochips 925 Biocomposite 358, 452 platforms 479... [Pg.960]

Data-informed calibration of experts in Bayesian framework... [Pg.76]

The dyes used in the prqjaiaticBi rf illidt pills can be incDipo-lated into drug analysis, tn a recent study, researchers used capillary electrophoresis to evaluate 14 dyes as part of a drug-profiling application that included Bayesian statistical analysis. The study craiducted in Europe, focused on dyes develop>ed for use in foodstuffs. Many erf ttiese dyes, which are acidic and water soluble, are available in the United States and Canada. In die study IXDQs were in the ran of 0.008-0.06 ppm and lOD was reported at 0.008 ppm. Calibration curves (an internal standard method) had about... [Pg.513]

Jackson, C.H., Jit, M., Sharpies, L.D. De Angelis, D. 2013. Calibration of Complex Models through Bayesian Evidence Synthesis A Demonstration and Tutorial. Medical Decision Making. [Pg.1598]

The derivation of functional relationships between independent variables, i.e., a concentration or amount proportional quantity and dependent variables - the response - belongs to the daily work of an analytical chemist. The functional relation has to be established in the calibration step and the concentration of an unknown sample can be estimated by its inverse application. Really both the dependent and independent variables are superimposed by error. Statistical methods accounting for errors in both responses (y) and concentrations (x) can hardly be applied if only a small sample size is available because the estimates become poor. Furthermore, in comparison to the Bayesian approach the incorporation of prior knowledge or subjective aspects with respect to the uncertainty of the data is carried out more easily by fuzzy methods. Results relying on the Bayesian approach can be doubtful if standard model assumptions do not hold. ... [Pg.1097]

The objective of model updating (often also referred to as parameter estimation) is to calibrate unknown system properties which appear as parameters in numerical models, based on actually observed behavior of the system of interest. In Bayesian model updating, this is performed in a probabilistic uncertainty quantification framework PDFs representing the uncertainty on the model parameters are updated through the experimental data this procedure is described briefly below. [Pg.1523]

Kennedy MC, O Hagan A (2001) Bayesian calibration of computer models. J R Stat Soc Ser B (Stat Method) 63(3) 425 f64... [Pg.1545]

Bayesian statistics age modelling Chronology Radiocarbon calibration... [Pg.2021]

When dealing with radiocarbon dates, Bayesian statistics provides a useful framework for the integration of information from different sources and is widely used in archeology and environmental science. This is partly because of the non-normal nature of the uncertainties in calibrated radiocarbon measurements but also because such methods are very flexible and allow the inclusion of many different kinds of underlying model. [Pg.2026]

Buck CE, Christen JA, James GN (1999) BCal an on-line Bayesian radiocarbon calibration tool. Internet Archaeol 7... [Pg.2031]


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