Dexamethasone Caffeine

Noninterfering amoxicillin, caffeine, dexamethasone, gentamicin, hydrocortisone, indo-methacin, metoclopramide, midazolam, theobromine, theophylline, tolazoline... 

Figure 6.17 The classification of 42 drugs in the (solubility-dose ratio, apparent permeability) plane of the QBCS. The intersection of the dashed lines drawn at the cutoff points form the region of the borderline drugs. Key 1 acetyl salicylic acid 2 atenolol 3 caffeine 4 carbamazepine 5 chlorpheniramine 6 chlorothiazide 7 cimetidine 8 clonidine 9 corticosterone 10 desipramine 11 dexamethasone 12 diazepam 13 digoxin 14 diltiazem 15 disopyramide 16 furosemide 17 gancidovir 18 glycine 19 grizeofulvin 20 hydrochlorothiazide 21 hydrocortisone 22 ibuprofen 23 indomethacine 24 ketoprofen 25 mannitol 26 metoprolol 27 naproxen 28 panadiplon 29 phenytoin 30 piroxicam 31 propanolol 32 quinidine 33 ranitidine 34 salicylic acid 35 saquinavir 36 scopolamine 37 sulfasalazine 38 sulpiride 39 testosterone 40 theophylline 41 verapamil HC1 42 zidovudine.

A false-positive dexamethasone-suppression test has been associated with ingestion of caffeine equivalent to 4-5 cups of coffee (58). 

Lee MA, Flegel P, Cameron OG, Greden IF. Chronic caffeine consumption and the dexamethasone suppression test in depression. Psychiatry Res 1988 24(l) 61-5. 

Clinically important, potentially hazardous interactions with acetylcysteine, adenosine, aprepitant, aripiprazole, buprenorphine, caffeine, charcoal, clarithromycin, clobazam, dorazepate, clozapine, darunavir, dasatinib, delavirdine, dexamethasone, diltiazem, doxacurium, erythromycin, felodipine, fesoterodine, fosamprenavir, imatinib, influenza vaccines, lacosamide, lapatinib, levetiracetam, lopinavir, methylprednisolone, midazolam, nelfinavir, nilotinib, piracetam, prednisolone, propoxyphene, ritonavir, rivaroxaban, rufinamide, solifenacin, St John s wort, telithromycin, temsirolimus, terbinafine, tolvaptan, troleandomycin, verapamil, voriconazole... 

The efflux transporter P-glycoprotein (P-gp) has been proposed as a potential therapeutic target for AD [439]. Approximately 10-35 % decrease in 125I-Ap(i 0) intracellular accumulation was observed in cells treated with rifampicin, dexamethasone, caffeine, verapamil, hyperforin, p-estradiol, and pentylenetetrazole, drugs known to induce P-gp expression [439],... 

Also analyzed acepromazine, acetaminophen, acetophenazine, albuterol, aminophylline, amitriptyline, amobarbital, amoxapine, eunphettunine, amylocaine, antipyrine, aprobar-bital, aspirin, atenolol, atropine, avermectin, barbital, benzocaine, benzoic acid, benzotro-pine, benzphetamine, berberine, bibucaine, bromazepan, brompheniramine, buprenor-phine, buspirone, butabarbital, butacaine, butethal, caffeine, carbamazepine, carbromal, chloramphenicol, chlordiazepoxide, chloroquine, chlorothiazide, chloroxylenol, chlorphe-nesin, chlorpheniramine, chlorpromazine, chlorpropamide, chlortetracycline, cimetidine, cinchonidine, cinchonine, clenbuterol, clonazepam, clonixin, clorazepate, cocaine, codeine, colchicine, cortisone, coumarin, cyclazocine, cyclobenzaprine, cyclothiazide, cyheptamide, cymarin, danazol, danthron, dapsone, debrisoquine, desipramine, dexamethasone, dex-... 

Simultaneous acetaminophen, aldosterone, allopurinol, amitriplyline, caffeine, calcitriol, cephalothin, chlordiazepoxide, chlorothiazide, corticosterone, cortisone, dexamethasone, diazepam, ephedrine, ethinyl estradiol, furosemide, hydrocortisone, ibuprofen, imipra-mine, indomethacin, mechlorethamine, methylprednisone, metolazone, nandrolone, naproxen, phenacetin, phenobarbital, phen3doin, probenecid, progesterone, propranolol, sulfasalazine, testosterone, theophylline, vincristine... 

The results of the dexamethasone suppression test can be falsified by the acute ingestion of caffeine but chronic caffeine use does not appear to have an effect. 

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