Butadiene, hexachloro

Synonyms AI3-05773 BRN 1766570 C 46 CCRIS 326 Dolen-pur EINECS 201-765-5 GP-40-66 120 HCBD Hexachlorbutadiene 1,1,2,3,4,4-Hexachlorobutadiene 1,3-Hexachloro-butadiene Hexachloro-1,3-butadiene 1,1,2,3,4,4-Hexachloro-l,3-butadiene NSC 3701 Per-chlorobutadiene RCRA waste number U128 UN 2279. 

Synonyms Hexachloro-1,3-butadiene Hexachloro-buta-1,3-diene (HCBD) Perchlorobutadiene Chemical/Pharmaceutical/Other Class Chlorinated hydrocarbon... 

Semi- or non-volatile chlorinated organic Compounds, hexachloro-butadiene, hexachloro-cyclopentadiene, octa. chlorocyclopentadiene, hexachlorobenzene Extractions performed on homogeniser using hexane, hexane -benzene or hexane -toluene Purge and trap method, recoveries 88-125% 0.1 ppb [189]... 

Hexafluoro-2,5-dihydrofuran [24849-02-3] is distilled into sulfur trioxide [7446-11-9] at 25°C. Addition of trimethyl borate [121-43-7] initiates a reaction which upon heating and distillation leads to a 53% yield of difluoromaleic anhydride. Dichloromaleic anhydride [1122-17-4] can be prepared with 92% selectivity by oxidation of hexachloro-1,3-butadiene with SO in the presence of iodine-containing molecules (65). Passing vaporized... 

Bosma TNP, FHM Cottaar, MS Posthumus, CJ Teunis, A van Veidhuizen, G Schraa, AJB Zehnder (1994) Comparison of reductive dechlorination of hexachloro-l,3-butadiene in Rhine sediments and model systems with hydroxocobalamin. Environ Sci Technol 28 1124-1128. 

Chromium compounds interact synergistically or antagonistically with many chemicals. For example, potassium dichromate administered by subcutaneous injection potentiated the effects of mercuric chloride, citrinin, and hexachloro-1,3-butadiene on rat kidneys (USPHS 1993). Chromium effects were lessened by ascorbic acid and Vitamin E, and N-acetyl cysteine was effective in increasing urinary excretion of chromium in rats (USPHS 1993)... 

PROPANEDIAHINE TRIMETHYL SILANE TETRACHLOROTHIOPHENE HEXACHLORO-1,3-BUTADIENE OCTAFLUORO-2-BUTENE OCTAFLUOROCYCLOBUTANE DECAFLUOROBUTANE BUTADIYNECBIACETYLENE) MALEIC ANHYDRIDE VINYLACETYLENE... 

In a subsequent study, the additivity assumption (dose addition) was tested, using the similarly acting nephrotoxicants tetrachloroethylene, trichloroethylene, hexachloro-1,3-butadiene (HCBD), and l,l,2-trichloro-3,3,3-trifluoropropene (Jonker et al. 1996). The compounds were given to female rats by daily oral gavage for 32 days either alone, at the LONEL and NONEL (= LONEL/4), or in combinations of four (at the NONEL and LONEL/2) or three (at the LONEL/3) (see Table 10.9). 

When hexachloro-1,3-butadiene (81) is reacted with four equivalents of n-butyllithium in diethyl ether, a series of lithiation and elimination reactions gives l,4-dilithio-l,3-butadiyne (82) in good yields (Scheme 30). Ijadi-Maghsoodi and Barton verified this by derivatization with various chlorosilanes in yields up to 94%". ... 

Baggett JM, Berndt WO. 1984. Renal and hepatic glutathione concentrations in rats after treatment with hexachloro-1,3-butadiene and citrinin. Arch Toxicol 56 46-49. 

Ban M, de Ceaurriz J. 1988. Probenecid-induced protection against acute hexachloro-1,3-butadiene and methyl mercury toxicity to the mouse kidney. Toxicol Lett 40 71-76. 

Davis ME. 1988. Effects of AT-125 on the nephrotoxicity of hexachloro-1,3-butadiene in rats. Toxicol AppI Pharmacol 95 44-52. 

Davis ME, Berndt WO, Mehendale HM. 1980. Disposition and nephrotoxicity of hexachloro-1,3-butadiene. Toxicology 16 179-191. 

Dekant W, Schrenk D, Vamvakas S, et al. 1988a. Metabolism of hexachloro-1,3-butadiene in mice in wVoand in vitro evidence for activation by glutathione conjugation. Xenobiotica 18 803-816. 

Dekant W, Vamvakas S, Henschler D, et al. 1988b. Enzymatic conjugation of hexachloro-1,3-butadiene with gultathione. Formation of 1 -(Glutathion-S-yl)-l, 2,3,4,4-pentachlorobuta-1,3-diene and 1,4-... 

Harleman JH, Seinen W. 1979. Short-term toxicity and reproduction studies in rats with hexachloro-(1,3)-butadiene. Toxicol AppI Pharmacol 47 1-14. 

Hook JB, Ishmael J, Lock EA. 1983. Nephrotoxicity of Hexachloro-1 3-butadiene in the rat The effect of age, sex, and strain. Toxicol AppI Pharmacol 67 122-131. 

KastI PE, Hermann EA. 1983. Quantitative gas chromatographic determination of hexachloro-1,3-butadiene in whole rat blood at part per trillion levels. Journal of Chromatography 280 390-393. 

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