Bupleurum

This alcohol, of the formula CjoHj O, occurs in the essential oil Bupleurum fi-uticomni, from which it was isolated hy Francesconi and Semagiottod It was separated hy means of its phthalic acid ester, and is an oil of faint rose odour, having the following characters —... 

Hasen-klee, m. rabbit-foot clover, hare s-foot trefoil, -kohl, m. wood sorrel, -ohrlein, n. hare s-ear (Bupleurum). -schwanz, m, hare s-tail grass. 

A few examples of pure arabinans with effect in the complement system have been isolated from, for example, the fruits of Ziziphus jujuba (a-2,5-arabinofuranan) and from the roots of Bupleurum falcatum (Q -3,5-arabino-furanan-Q -l,4-glucan complex) [12,13]. 

Figure 6 from Carbohydrate Research, vol 311, Sakurai MH, Kiyohara H, Matsumoto T, TsumurayaY, Hashimoto Y, Yamada H (1998) Characterization of antigenic epitopes in anti-ulcer pectic polysaccharides from Bupleurum falcatum L. using several carbohy-drases. p 219-p229, all with permission from Elsevier... 

Allium cepa) [5], kiwi frait Actinidia deliciosa) [6], Bupleurum falcatum roots [7] and Arabidopsis thaliana [8]. 

A significant advance in the understanding of the anti-inflammatory properties of Bupleurum fruticescens has been provided by Prieto et al. (36). The showed that a methanol extract from the aerial parts had a significant effect on 5-lipoxygenase activity, inhibiting both LTB4 and 5(S)-HETE production, with IC50 values of 112 and 95 (xg/mL, respectively. At concentrations of 200 (Xg/mL, the extract inhibited COX-1 (90%) and elastase activities (54%). What are the principles involved here, saponin ... 

Prieto JM, Giner RM, Recio MC, Manez S, Rios JL. Dual inhibition of cyclooxygenase-1 and 5-lipoxygenase by aerial part of Bupleurum fruticescens methanol extract. Fitoterapia 2004 75 179-186. 

Saudi Arabia. Hot water extract of the dried rhizome is taken orally as a stomachic, a diuretic, a carminative, and an antiemetic and used externally as an antiseptic, anesthetic, and astringent . South Korea. Hot water extract of the dried rhizome is taken orally as an abortifa-cient . Hot water extract of the rhizome, together with Bupleurum falcatum, Scutellaria baicalensis, Panax ginseng, Glycyrrhiza glabra, Zizyphusjujuha, and Pinellia tuberosa, is taken orally for tonsillitis, otitis media, tuberculosis, common cold, liver disorders, chills, fevers, and chest pains . 

Alanine aminotransferase inhibition. Decoction of dried rhizome, taken orally by human adults of both sexes at a dose of 7.5 g/day for 6 months, was active on 80 patients with hepatitis B antigen-positive chronic hepatitis. The study was conducted with a prescription that consists of B.upku-rum falcatum Bupleurum falcatum (Rt), Scutellaria baicalensis Scutellaria baicalensis (Rt), Pinellia ternata (Tu), Zizyphus jujuba (Fr), Panax ginseng (Rt), and Glycyrrhiza glabra (Rh) . 

Degranulation inhibition. Hot water extract of the rhizome, in cell culture at a concentration of 0.1 mg/mL, was active vs compound 48/40-induced degranulation of mast cells. A mixture of Bupleurum falcatum, Pinellia ternata, Poria cocos, Scutellaria bai-... 

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