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Buccal/sublingual systemic drug delivery

The term mucoadhesion is commonly used to describe an interaction between the mucin layer, which lines the entire GI tract, and a bioadhesive polymer, which could be natural or synthetic in origin.From the oral delivery standpoint, these systems are used to immobilize and localize a drug delivery device in the selected regions of the GI tract, which could be an oral cavity (buccal and sublingual routes), the esophagus, stomach, small intestine, or colon (oral route). For the most part, research in this area has focused on the design of polymeric micro- and nanoparticulate systems that use hydrophilic polymers, primarily due to their propensity to interact with the mucosal surface. ... [Pg.1253]

Senel, S. Rathbone, M.J. Cansiz, M. Pather, I. Recent developments in buccal and sublingual delivery systems. Expert Opin. Drug Deliv. 2012, 9 (6), 615-628. [Pg.1249]

See other pages where Buccal/sublingual systemic drug delivery is mentioned: [Pg.193]    [Pg.152]    [Pg.2664]    [Pg.145]    [Pg.39]    [Pg.176]    [Pg.189]    [Pg.197]    [Pg.203]    [Pg.2]    [Pg.67]    [Pg.988]    [Pg.2692]    [Pg.2698]    [Pg.3653]    [Pg.455]    [Pg.464]    [Pg.464]    [Pg.370]    [Pg.13]    [Pg.144]    [Pg.199]    [Pg.18]    [Pg.188]    [Pg.346]    [Pg.1232]   
See also in sourсe #XX -- [ Pg.464 ]



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Buccal

Buccal delivery systems

Buccal drug delivery

Sublingual

Sublingual delivery

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