Brussels glucosinolates

Fig. 4.1 Sinigrin is an aliphatic glucosinolate that occurs at significant levels in the human diet, notably in mustard and Brussels sprouts. When brought into contact with myrosinase, derived either from plant cells or from colonic bacteria, it is broken down to yield a variety of products including the acrid, volatile, biologically active compoimd...

FENWICK G R, GRIFFITHS N M and HEANEY R K (1983) Bittemess in Brussels sprouts (Brassica oleracea L. vat gemmifera) The role of glucosinolates and their breakdown products , J Sci Food Agric, 34 73-80. 

VAN DOORN H E, VAN DER KRUK G C, VAN HOLST G-J, RAAIJMAKERS-RUIJS N C M E, POSTMA E, GROENEWEG B and JONGEN w H F (1998) The glucosinolates sinigrin and progoitrin are important determinants for taste preference and bitterness of Brussels sprouts , J Sci Food Agric, 78 30-38. 

WALLiGM A, KINGSTON s, STAACK R and JEFFEREY E H (1998) Induction of rat pancreatic glutathione S-transferase and qitinone reductase activities by a mixture of glucosinolate breakdown derivatives foimd in Brussels sprouts . Food Chem Toxicol, 36 365-73. 

STAACK R, KINGSTON s, WALLiG M A and JEFFERY E H (1998) A Comparison of the individual and collective effects of four glucosinolate breakdown products from Brussels sprouts on induction of detoxification enzymes , Toxicol Appl Pharmacol, 149 17-23. 

Tian Q, Rosselot RA, Schwartz SJ (2005) Quantitative determination of intact glucosinolates in broccoli, broccoli sprouts, brussels sprouts, and cauliflower by high-performance hquid chromatography-electrospray ionization-tandem mass spectrometry. Anal Biochem 343 93-99... 

The buds and the leaves (less often) of the Brussels sprout plant (Brasska olera-cea var. gemmifera) are eaten cooked with the main meal. In Brussels sprouts, breakdown products from glucosinolates are dominant and represent about 80-90% of the volatiles in headspace samples [176]. The residual volatiles are mostly sulfur compounds [176]. Compounds likely to be associated with the aroma of Brussels sprouts are 2-propenyl isothiocyanate, dimethyl sulfide, dimethyl disulfide and dimethyl trisulfide (Table 7.6) [35,176]. 

Glucosinolates from Brassicaceae (Cruciferae) e.g. Brassica napus, Brassica oleraceae (Brussels sprouts)... 

Figure 7.2 Distribution pattern of major glucosinolates in various vegetables belonging to Brassica oleracea. Fresh samples of the edible part of the vegetable were freeze-dried and analyzed for glucosinolate content by previously published methods. Data are mean pmols glucosinolate/g dry weight vegetable 50 varieties of broccoli, 4 varieties of Brussels sprouts, 6 varieties of cabbage, 3 varieties of cauliflower, and 2 varieties of kale.

Broccoli, cabbage, Brussels sprouts, horseradish, and mustard contain unique chemicals called glucosinolates and isothiocyanates. These chemicals are respon-... 

An enzyme involved in cell cycle control has been identified as the target of a compound supplied by broccoli, cabbage, and Brussels sprouts. One of the glucosinolates of these foods is the source of a chemical called indole 3-carbinol. Indole-3-carbinol enters the cell and influences the activity of a spixiat protein kinase that is used to control the cell cycle. The chemical prevents the synthesis of the enzyme, and thus reduces its activity. The action of this protein kinase (cyclin-dependent protein kinase 6) normally functions to make the cell embark on the G phase of the cell cycle, and thus to stimulate progression through the cell cycle. The chronic decrease in activity of this protein kinase serves to prevent cell division, but also prevents spontaneous cancers. The effect of mdoJe-3-carbinol has been shown to occur in cultured cells, as well as in animals (Cover ef o/ 1998). 

Shepherd s purse contains glucosinolates, compounds present in many plants in the Brassicaceae family (e.g., cauliflower and Brussels sprouts). These compounds have been shown to cross the placenta and to be present in breast milk (Panter and James 1990). At high concentrations, glucosinolates inhibit iodine uptake by the thyroid, although at lower concentrations cancer-preventive effects have been shown (Stoewsand 1995). 

Carlson, D.G. et al. (1987) Glucosinolates in crucifer vegetables - Broccoli, brussels- sprouts, cauliflower, collards, kale, mustard greens, and x a )iJAmSocH( 1icuUla alSci 112(1), 173 178... 

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