Brain morphometry

Botteron, K.N., Raichle, M.E., Heath, A.C., and Todd, R.D. (2000) Twin study of brain morphometry in adolescent- or earlier-onset depression. Presented at Depression in the Twenty-first Century. Laguna Beach, CA ... 

McClure RK, Phillips I, Jazayerli R, Barnett A, Coppola R, et al. 2006. Regional change in brain morphometry in schizophrenia associated with antipsychotic treatment. Psychiatry Res 148(2-3) 121-132. 

Lochhead,R. A., Oquendo, M. A, Mann, J. J. and Parsey,R.V. Regional brain gray matter volume differences in bipolar disorder patients as assessed by optimized voxel-based morphometry. Biol. Psych. 55 1154-1162, 2004. 

Blanchard, J. D., Heyder, J., O Donnel, C. R., and Brain, J. D. Aerosol-derived lung morphometry Comparisons with a lung model and lung function indexes. J. Appl. Physiol. 71 1216-1224, 1991. 

Hoogendijk WJ, Pool CW, Troost D, van Zwieten E, Swaab DF (1995) Image analyser-assisted morphometry of the locus coeruleus in Alzheimer s disease, Parkinson s disease and amyotrophic lateral sclerosis. Brain 118 ( Pt 1) 131-143. 

McDonald, C., Bullmore, E., Sham, P., Chitnis, X., Suckling, J., MacCabe, J., Walshe, M., Murray, R. M. 2005, Regional volume deviations of brain structure in schizophrenia and psychotic bipolar disorder computational morphometry study, Br.fPsychiatry, vol. 186, pp. 369-377. 

Csernansky JG, Joshi S, Wang L, Haller JW, Gado M, et al. 1998. Hippocampal morphometry in schizophrenia by high dimensional brain mapping. Proc Natl Acad Sci USA 95 11406-11411. 

Honea R, Crow TJ, Passingham D, Mackay CE. 2005. Regional deficits in brain volume in schizophrenia A meta-analysis of voxel-based morphometry studies. Am J Psychiatry 162 ... 

Honea R, Crow TJ, Passingham D, Mackay CE. Regional deficits in brain volume in schizophrenia a meta-analysis of voxel-based morphometry studies. Am. J. Psychiatry 2005 162 2233-2245. Kubicki M, Westin CF, McCarley RW, Shenton ME. The application of DTI to investigate white matter abnormalities in schizophrenia. Ann. N. Y. Acad. Sci. 2005 1064 134-148. White T, Kendi AT, Lehericy S, Kendi M, Karatekin C, Guimaraes A, Davenport N, Schulz SC, Lim KO. Disruption of hippocampal connectivity in children and adolescents with schizophrenia-a voxel-based diffusion tensor imaging study. Schizophr. Res. 2007 90 302-307. 

Lu et al. [101] used Tensor-based morphometry (TBM), a novel computational approach for visualizing longitudinal progression of brain atrophy, to determine whether cognitively intact elderly participants with the e4 allele demonstrate greater volume reduction than those with the e2 allele, and found that possession of the e4 allele is associated with greater temporal and hippocampal volume reduction well before the onset of cognitive deficits. 

Meisami E, Sendera TJ. 1993. Morphometry of rat olfactory bulbs stained for cytochrome oxidase reveals that the entire population of glomeruli forms early in the neonatal period. Brain Res Dev Brain Res 71 253-257. 

Aboitiz F, Scheibel AB, Zaidel E (1992) Morphometry of the Sylvian fissure and the corpus callosum, with emphasis on sex differences. Brain 115 1521-1541. 

Kassubek J, Unrath A, Huppertz HJ, Lule D, Ethofer T, Sperfeld AD, Ludolph AC (2005) Global brain atrophy and corticospinal tract alterations in ALS, as investigatedby voxel-based morphometry of 3-D MRI. Amyotroph Lateral Scler Other Motor Neuron Disord 6 213-220... 

Ten pm thick sections of unfixed frozen brains can be cut on a cryostat and observed using a fluorescence microscope with a TRITC filter. EB appears as a red area that can be quantified by morphometry. EB staining can be combined with immunohisto-chemical staining for any of the markers reported in Table 1 and/ or blood vessel markers. See Note 5. 

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