Brain development lipid nutrition

Crawford MA, Sinclair AJ. Nutritional influences in evolution of mammalian brain. In Lipids, Malnutrition and the Developing Brain. Ciba Foundation Symposium. Associated Scientific, Amsterdam 1972, pp. 267-287. 

Martinez, M., and Ballabriga, A. (1987). Effects of parenteral nutrition with high doses of linoleaie on the developing human liver and brain. Lipids 22,133-138. 

Martinez, M. (1994) Polyunsaturated fatty acids in the developing human brain, red cells and plasma influence of nutrition and peroxisomal disease. Fatty acids and lipids biological aspects. (Galli, C., Simpolous, A.P. and Tremoli, E., eds.). World Rev. Nutr. Diet. Karger, vol. 75, pp. 70-78. 

By feeding nutritionally adequate diets, dietary intake of 18 2n-6, 18 3n-3, or the proportion of 18 2n-6 to 18 3n-3, particularly during development, has been shown to influence the content of long-chain polyunsaturated fatty acids in membrane lipids by changing the composition of the whole brain, oligodendrocytes, myelin, astrocytes mitochondrial, microsomal, and synaptosomal membrane (Bourre et al., 1984 Foot et al., 1982 Lamptey Walker, 1976 Tahin et al., 1981). Feeding diets with a 18 2n-6 to 18 3n-3 fatty acid ratio between 4 1 and 7 1 to rats from birth to 1, 2, 3, and 6 wk of... 

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