Boyer, Herbert

Boxing dental wax, 8 299 specification, 8 300t Box-type mixer-settler, 10 774 Boyer, Herbert, 11 11 BPA diacetate, transesterification of, 19 816. See also Bisphenol A (BPA)... 

Cohen, Stanley Chang, A. C. Y. Boyer, Herbert et al. (1973). Construction of Biologically Functional Bacterial Plasmids In Vitro. Proceedings of the National Academy of Sciences 70 3240-3244. 

Boyer, Herbert Wayne (b. 1936) American biochemist and genetic engineering pioneer who showed that, by using an enzyme called an endonuclease, a DNA ring (a plasmid) from a bacterium could be inserted into the DNA of another bacterium or that of a toad. He was then able to clone the hybrid DNA by allowing bacteria containing it to reproduce. Boyer s achievement led to the commercial production of insulin and other valuable proteins. 

The first biologically functional chimeric DNA molecules constructed in vitro were assembled from parts of different plasmids in 1973 by Stanley Cohen, Annie Chang, Herbert Boyer, and Robert Helling. These plasmids were used to transform recipient E. coli cells transformation means the uptake and repli-... 

Genentech was founded in 1976 by scientist Herbert Boyer and the venture capitalist Robert Swanson. Headquartered in San Francisco, it employs almost 5000 staff worldwide and has 10 protein-based products on the market. These include hGHs (Nutropin, Chapter 11), the anti-body-based products Herceptin and Rituxan (Chapter 13) and the thrombolytic agents Ac-tivase and TNKase (Chapter 12). The company also has 20 or so products in clinical trials. In 2004, it generated some US 4.6 billion in revenues. 

Robert A. Swanson and biochemist Dr Herbert W. Boyer, and the changes in state and federal laws (the 1980 Bayh-Dole Act) paved the way for universities and academicians to participate in fostering business alliances and creating new companies. 

Herbert Boyer and Stanley Cohen construct first recombinant DNA molecule and reproduce... 

Stanley Cohen and Herbert Boyer awarded first patent for cloning a gene Paul Berg, Walter Gilbert, and Frederick Sanger awarded Nobel Prize in chemistry for the creation of the first recombinant molecule... 

Dawkins realized that the genes were evolving here, not us. We are just the vessel, and Dawkins realized the significance of replicators in general. After that, the field opened up rather widely, and must include Stan Cohen and Herbert Boyer, whose notion, compormded in 1973 in a late-night deli in Oahu, of artificially replicating specific genes underlies most of the subject matter in this rather important series of books. 

The initial scientific discovery by Stanley Cohen and Herbert Boyer, leading to the new technology in 1973, provided the basic technique for recombinant DNA. As this discovery became increasingly understood, its commercial implications became recognized. New firms were created to employ this new technology. 

The age of biotechnology started in the USA with the foundation of the first biotech company. Genentech was founded by the renowned biochemist Herbert Boyer and the young visionary venture capitalist Robert Swanson. (Of the... 

It has now been more than fifteen years since Robert Swanson, a young man who understood both finance and science, invited Herbert Boyer, a shy molecular biologist at the University of California, San Francisco, out for a beer. Swanson described his vision to Boyer that the techniques and ideas that Boyer had devised... 

Stanley Cohen and Herbert Boyer Stanford, CA, USA method of recombination of DNA developed... 

Stanley Cohen and Herbert Boyer, genetic engineering in the 1980s... 

In 1976 Herbert Boyer, one of the discoverers of the rDNA technique and a member of the faculty at UCSF, and Robert Swanson, a venture capitalist with MIT degrees in chemistry and business, formed Genentech. As Swanson put it, in terms reminiscent of those of Landau in chemicals, For Genentech, the strategy from the beginning was to be able to make and sell our own products. Therefore we needed not only to generate products but to manufacture them and build the marketing force to sell them. ... 

Genetic engineering is the manipulation of an organism s DNA. In 1976, with venture capitalist Robert Swanson, Herbert Boyer founded a company called Genentech to use recombinant DNA technology to produce medicines. In 1978, the company successfully inserted the human insulin gene into E. coli bacteria and then grew them to produce commercial amounts of insulin. 

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