Blood metabolites

Cobbaert C, Morales C, van Fessem M, Kem perman H (1999) Precision and accuracy and linearity of radiometesEML 105 whole blood metabolite biosensors. Ann Clin Biochem 36.730-738. 

The proposed metabolic pathway for 2-hexanone is based on blood metabolites identified during intraperitoneal studies in guinea pigs (DiVincenzo et al. 1976) and oral studies in rats (DiVincenzo et al. 1977). The metabolite 2,5-hexanedione has also been found in human serum after inhalation exposure (DiVincenzo et al. 1978). Because studies in rats exposed to 2-hexanone have indicated a strong relationship between the concentration of 2,5-hexanedione in the urine and the onset of neuropathic symptoms (Eben et al. 1979), it would be useful to also have this information for humans. 

The determination of diazepam in plasma with detection limits of 0.03-0.2 fjLg/mh by cathode ray [189] and pulse polarography [174,190] has been described. The first reported pulse assay [174] differs from the other polarographic assays [189,190] in that a more polar solvent is employed to ensure quantitative extraction, followed by TLC separation and determination of diazepam and its major blood metabolite, N-desmethyldiazepam, to ensure specificity. 

Hossain, S.M. and Blair, R. (2007) Chitin utilization by broilers and its effect on body composition and blood metabolites. British Poultry Science 48, 33-38. 

Blood Metabolites in Insulin Insufficiency For the patient described in Problem 12, predict the levels of the following metabolites in his blood before treatment in the emergency room, relative to levels maintained during adequate insulin treatment (a) glucose (b) ketone bodies (c) free fatty acids. 

Fernandez JM, Croom WJ, Johnson AD, et al. 1988. Subclinical ammonia toxicity in steers effects on blood metabolite and regulatory hormone concentrations. J Anim Sci 66(12) 3259-3266. 

Dietary fat source also had no effect on the concentration of blood metabolites during rest, exercise, or recovery (Table VIII). Serum glucose remained within normal physiological limits during all phases. Although there was a small decrease in serum glucose due to exercise, the values did not differ significantly from those while at rest. Plasma lactate and pyruvate increased... 

Melendez, R, J.R Goff, C.A. Risco, L.R Archhald, R. Littell, and G.A. Donovan. Effect of Monensin Controlled-Release Capsule on Rumen and Blood Metabolites in Florida Holstein Transition Cows, jjx 2- 7 - 4182—4189 (2004). 

A number of mechanisms have been invoked to explain the activation of the hypothalamic centers. These mechanisms can be categorized as changes in body temperature, changes in the concentration of blood metabolites (glucose, fats, amino acids, and even water), and efferent nervous impulses originating in the viscera. The most popular theory is that proposed by Mayer [151-153] and referred to as the hypothala-... 

Identification of a Blood Metabolite of Methsuximide by GLC Mass Spectrometry... 

Yang WZ, Ametaj BN, Benchaar C, He ML, Beauchemin KA (2010) Ciimamaldehyde in feedlot cattle diets intake, growth performance, carcass characteristics, and blood metabolites. J Arum Feed Sd 88 1082-1092... 

Lila ZA, Mohammed N, Kanda S et al (2005) Sarsaponin effects on ruminal fermentation and microbes, methane production, digestibility and blood metabolites in steers. Asian-Aust J Anim Sci 18 1746-1751... 

Wikoff WR, Anfora AT, Liu J et al (2009) Metabolomics analysis reveals large effect of gut microflora on mammalian blood metabolites. Proc Natl Acad Sd USA 106 3698-3703 Yih A, Aisa HA, Maksimov VV et al (2009) Chemical composition and antimicrobial activity of essential oQ from seeds of Anethum graveolens growing in Uzbekistan. Chem Nat Comp 45 280-281... 

Isoproterenol (Iso) increased avUCP expression (+67% after I h of stimulation), as previously observed in vivo in chicken muscle, but to a greater extent (9 fold-increase Joubert et al, 2010). This discrepancy could be explained by the concomitant effect of isoproterenol on other factors regulating muscle metabolism in vivo, such as plasma thyroid hormones or blood metabolites that could not be investigated here. The use of fatty acid supplement (FA) induced a delayed increase in avUCP expression (+54% after 2 h of stimulation) and was associated with stronger activations of p38 MAPK and AMPK than with isoproterenol. 

Miettinen, H. and P. Huhtanen, 1996. Effects of the ratio of ruminal propionate to butyrate on milk yield and blood metabolites in dairy cows. J. Dairy Sci. 79, 851-861. [2]... 

Van Knegsel, ATM., H. van den Brand, J. Dijkstra, W.M. van Straalen, R. Jorritsma, S. Tamminga, S. and B. Kemp, 2007. Effect of glucogenic vs. lipogenic diets on energy balance, blood metabolites, and reproduction in primiparous and multiparous dairy cows in early lactation. J. Dairy Sci. 90, 3397-3409. 

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