Blood, analysis sugar

A number of important methods are based on the oxidation of sugars by ferricyanide ion in alkaline solution. The method is open to the same objections as the copper reduction methods, namely, the lack of a stoichiometric reaction and the dependence of the method on arbitrarily chosen conditions. The ferricyanide may be used to titrate the sugar solution directly by the use of picric acid or of methylene blue as an indicator. Or, the reduced ferrocyanide may be precipitated as the zinc salt, and the excess ferricyanide determined iodometrically. The Hagedom-Jensen method and the Hanes modification utilize the latter procedure. In the Folin-Malmros micro method, Prussian blue is formed and determined colorimetrically. Extensive application of the ferricyanide method has been made in the determination of the diastatic power of amylase preparations and in blood analysis. 

For the detection of cystic fibrosis, which is a quantitative analysis, the situation is different because such an analysis is performed only in the hospital environment. This requires that the conditions to execute such a test with the sensor system can be chosen and controlled in such a way that possible interference is avoided. In addition, for cystic fibrosis detection, the analyst is interested in the electrolyte concentration of the sweat, regardless of how this sweat formation was obtained (high temperature, exercise), with the implication that the sources of interference are much less for cystic fibrosis detection than was the case for the detection of low sugar level in the blood. The complication in this type of analysis is that it is not enough to... 

Elementary analysis of B substance (G4) showed 41% carbon, 6.6% hydrogen, 5.7% nitrogen, and 7% acetyl. The same sugars and amino sugars were again found, including 17.9% fucose, as well as the same 11 amino acids. However, content of hexosamine was lower (20-22% only) as compared to 33-37% in blood group substances A, H, and Le. ... 

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