Block Copolymer Micelles Gohy

Gohy, J.F. Lohmeijer. B.G.G. Schubert, U.S. Reversible metallo-supramolecular block copolymer micelles containing a soft core. Macromol. Rapid Commun. 2002, 23. 555. 

H. Huang, R. Hoogenboom, M. A. M. Leenen, P. Guillet, A. M. Jonas, U. S. Schubert and J. F. Gohy, Solvent-induced morphological transition in corecross-linked block copolymer micelles , J Am Chem Soc, 2006,128,3784-8. 

Biltun, V., Armes, S.P., Bfllingham, N.C. and Tuzar, Z. (1999) Formation of block copolymer micelles and reverse micelles in aqueous solution. ACS Polym. Prepr. (Div. Polym. Chem.), 40(2), 261-262. Antoun, S., Gohy, J.F. and Jerome, R. (2001) MiceUization of quaternized poly(2-dimethyl-aminoethyl methacrylate)-fc-PMMA copolymer in water. Polymer, 42,3641-3648. Ossenbach-Sauter,M. (1981) Emulsifying properties of block copolymers, water-in-water polymeric emulsions. PhD Thesis, University of Haute Alsace, France. 

J.F. Gohy, and Y. Zhao, Photo-responsive block copolymer micelles Design and behavior, Chem Soc Rev, 42 (17), 7117-29,2013. 

Gohy JF, Lohmeijer BGG, Schuhert US (2002) Metallo-supramolecular block copolymer micelles. Macromolecules 35 4560-4563... 

Gohy, J.F., Zhao, Y. Photo-responsive block copolymer micelles design and behavior. Chem. Soc. Rev. 42, 7117-7129 (2013)... 

Meier MAR, Gohy J-F, Fustin C-A, Schubert US (2004) Combinatorial synthesis of starshaped block copolymers host-guest chemistry of unimolecular reversed micelles. J Am Chem Soc 126 11517-11521... 

Gohy JE, Lohmeijer BGG, Alexeev A, Wang XS, Manners 1, Winnik MA, Schubert US (2004) Cylindrical micelles from the aqueous self-assembly of an amphiphilic poly(ethylene oxide)-b-poly(ferrocenylsilane) (PEO-b-PES) block copolymer with a metallo-supramolecular linker at the block junction. Chem Eur J 20 4315 323... 

CAN Can, A., Hoppener, S., Guillet, P., Gohy, J.-F., Hoogenboom, R., and Schubert, U.S., Upper critical solution temperature switchable micelles based on polystyrene-6/oc -poly(methyl acrylate) block copolymers, J. Polym. Sci. Part A Polym. Chem., 49, 3681,2011. 

Detailed overviews on the micellisation of amphiphilic copolymers in organic solvents are provided in the reviews of Riess [1], Gohy [2], Hamley [7] and Chu et al. [101]. Apparently, a wide range of styrene, acrylate or methacrylate and diene-based block copolymers have been investigated, while AB diblock and ABA triblock architectures have been systematically compared. One of the main conclusions is that the formation of micelles in organic solvents can generally be considered as an entropy-driven process. 

Amphiphilic block copolymers with one ionic block constitute an intriguing class of macromolecules, since their self-assembly in aqueous solution usually leads to the formation of spherical micelles with a hydrophobic core and a polyelectrolyte corona. These micelles are particularly interesting because the intrinsic properties of their polyelectrolyte corona are strongly influenced by many parameters like pH, salt concentration, degree of dissociation, polar interactions and so on. Moreover, they can be considered as a model to spherical polyelectrolyte brushes and thus provide a unique opportunity to study polyelectrolyte properties in high concentration conditions. The micellisation behaviour of ionic amphiphilic copolymers has been reviewed by Riess [1], Gohy [2], Eisenberg et al. [112, 113], Forster et al. [138] and Cohen Stuart et al. [139]. 

Hu ZJ, Jonas AM, Varshney SK, Gohy JF (2005) Dilution-induced spheres-to-vesicles morphological transition in micelles from block copolymer/surfactant complexes. J Am Chem Soc 127 6526-6527. doi 10.1021/ja050053m... 

Gohy et al. studied the solution properties of micelles formed by two polystyrene-frZock-poly(2-vinylpyridine)-block-poly(ethylene oxide) (PS-b-P2VP- -PEO) copolymers in water by dynamic light scattering and transmission electron microscopy [92]. Spherical micelles were observed that consist of a PS core, a P2VP shell and a PEO corona. The characteristic sizes of core, shell and corona were found to depend on the copolymer composition. The micellar size increased at pH<5 due to P2VP block protonation (Fig. 19). 

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