Biomimetic complexes

The Picket-fence-oxygen Biomimetic Complex 3.3.2.1 Interplay Structure/Electronic State... 

In general, liquid-phase systems, encompassing homogeneous and biomimetic complexes, suffer from catalyst degradation in the oxidative environment, catalyst recovery problems, and contamination of the product. For these reasons, considerable efforts have been expended on immobilization of these systems on... 

In the biomimetic chemistry approach to bioinorganic modeling chemistry, well-defined, small molecule , metal complexes that reproduce aspects of the structure and/or function of a metalloprotein are synthesized. These biomimetic complexes generally include the same metal in a similar coordination... 

Besides biomimetic complexes, Jacobsen described particularly efficient bis (chromium-salen) catalyst 9 for the asymmetric ring-opening reaction of epoxides with azide (Scheme 9) [42]. The efficiency of this class of catalysts is attributed to a cooperative mechanism, both substrates being activated toward each other by their respective chromium atom. Of note, a less pronounced cooperative effect was initially demonstrated in an intermolecular manner using monomeric Cr(N3)-salen catalyst [43]. Jacobsen also showed that an analogous cooperative mechanism takes place using polymer-supported chiral Co(salen) complexes for the hydrolytic kinetic resolution of terminal epoxides [44, 45]. 

Wen F, Li C (2013) Hybrid artificial photosynthetic systems comprising semiconductors as light harvesters and biomimetic complexes as molecular cocatalysts. Acc Chem Res 46 (11 ) 2355-2364. doi 10.1021/ar300224u... 

A detailed analysis of the electronic structure of a mixed-valence biomimetic complex (47), obtained by oxidation of complex (48), has provided convincing evidence for the presence of a nitrogen atom in the dithiolate bridge of the active site of native... 

Another family of biomimetic complexes for proton reduction (and hydrogen oxidation) is the [Ni(PNP)2l complexes (Fig. 3) and modifications thereof [8, 9]. These complexes contain amines in the second coordination sphere that are... 

The application of biomimetic complexity generating reactions in natural products synthesis often enables access to structurally complex cores that may otherwise seem inconceivable. 

Figures and Tables in this chapter have appeared in [L.J. Daumann et al., Spectroscopic and mechanistic studies of dinuclear metallohydrolases and their biomimetic complexes Dalton Trans. 2014, 43, 910-928.]—Reproduced by permission of The Royal Society of Chemistry.

L. J. Daumann, Spectroscopic and Mechanistic Studies cf Dinuclear Metallohydrolases and Their Biomimetic Complexes, Springer Theses, DOI 10.1007/978-3-319-06629-5 l, Springer International Publishing Switzerland 2014... 

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