Biomedicine tissue engineering

The ultrathin fibrillar structures (fibers, medical threads, meshes, mats and scaffolds) are of utmost interest as the modem functional materials with specific properties such as the high surfaceA olume ratio of a single filament, effective surface modification, special physical-chemical behavior, and anomalous diffusion [1-5]. At the present time ultrathin fibers and articles on their base are efficiently applicable in biomedicine, tissue engineering, in filtration and separation processes, for composite design, in electronics, analytical supplies, sensor-based diagnostics, and in other iimovative applications [6-9]. 

One of the most exciting areas in basic research today involves the use of stem cells. These unique cells have the capability to transform and replenish the different tissue types that make up the body, and also represent the fundamental building blocks of human development. Recent advances in the areas of stem cell biology and tissue engineering, coupled with parallel achievements in molecular and cell biology, have paved the way to the development of a new field in biomedicine - regenerative medicine. 

Bronzio JD (2006) The biomedical engineering handbook. CRC, Boca Raton Fisher JP, Mikos AG, Bronzino JD (2007) Tissue engineering. CRC, Boca Raton Galaev I, Mattiasson B (2008) Smart polymers applications in biotechnology and biomedicine. CRC, Boca Raton... 

Design and fabrication of tissue-engineering scaffolds are currently an important research theme in biomedicine The structure of the scaffold should act as a template for 3D tissue growth it consists of a highly interconnected porous network with interconnections greater than 50 [im in diameter and pore diameters larger than 100 pm [290, 292]. 

He, A.J., Zheng, C.Q., Wang, T.F., Li, D.Y., Yin, L.X., Zheng Y. 2005. Dynamic three-dimensional reconstruction of tissue Doppler ultrasound heart images. Journal of Biomedicine Engineering 22(3) 570-574. (in Chinese). 

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