Biological significance, metabolic

Sunkara PS, Baylin SB, Luk GD (1987) Inhibition of Polyamine Metabolism Biological Significance and Basis for New Therapies.(eds) McCann PP, Peg AE, Sjoerdsma A. Academic Press, New York, p 121... 

As in the case of propachlor mercapturic acid sulfoxide, the biological significance of xenobiotic mercapturic acids that contain oxidized sulfur is not known. Casida et al. (39) have reported that sulfoxidation of some thiocarbamate herbicides is a beneficial step in the detoxication process. However, cysteine conjugates can exhibit adverse biological activities. Smith (40) has reviewed work on the metabolism of the toxic principle in kale and has shown that C-S lyase action on S-methylcysteine sulfoxide produces the toxic principle. Virtanen ( ) has reviewed the processes in other plants that lead to the production of compounds with biological activity from -substituted cysteine sulfoxides. 

W. Reutier, E. Kottgen, C. Bauer, and W. Gerok, Biological significance of sialic acid, in Sialic Acids. Chemistry, Metabolism, and Function, R. Schauer, ed., Springer-Verlag, Vienna, 1982, p. 263. 

DU VIGNEAUD, VINCENT (1901-1978). An American biochemist who won the Nobel prize lor chemistry in 1955. His work involved Ihe study of the metabolism of biologically significant sulfur compounds, which led to the finding of transmethylation in mammalian metabolism. He isolated and proved the structure of Ihe vitamin biotin, and synthesized penicillin, oxytocin, and the vasopressin hormone of the posterior pituitary. His education was at Rochester. Yale. St. Louis, and George Washington Universities. 

Stanley-Samuelson D. W., Jurenka R. A., Cripps C., Blomquist G. J. and deRenobales M. (1988) Fatty acids in insects Composition, metabolism and biological significance. Arch. Insect Biochem. Physiol. 9, 1-33. 

Garay AS, Czege J, Tolvaj L et al (1973) Biological significance of molecular chirality in energy balance and metabolism. Acta Biotheor 22 34-43... 

Inhaled dose The amount of an inhaled substance that is available for interaction with metabolic processes or biologically significant receptors after crossing the outer boundary of an organism (USEPA, 1997c). 

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