Bioimaging conjugates

Fig.l Schematic design of nanoparticie for bioimaging containing the fluorescent dye encapsuiated in an inorganic matrix Q surface modified with another sheii o and conjugated to biomoiecuies ... 

Santra S, Yang H, Dutta D, Stanley JT, Holloway PH, Tan WH, Moudgil BM, Mer-icle RA (2004) TAT conjugated, FITC doped silica nanoparticles for bioimaging applications. Chem Commun, pp 2810-2811... 

Amphiphilic polymer coatings are another method in which polymers are used to improve current bioimaging techniques. As described previously, polymer conjugation or coating can increase blood circulation, provide attachment sites for probe molecules, reduce toxicity and immunoge-nicity, prevent aggregation, and stabilize otherwise unstable... 

K. Li, B. liu. Polymer encapsulated conjugated polymer nanoparticles for fluorescence bioimaging, J. Mater. Chem. 22 (2012) 1257-1264. 

Detonation NDs have also been proposed for targeted fluorescent cellular bioimaging. " Mkandawire et al. prepared fluorescent cellular biomarkers by conjugating detonation NDs to antibodies and using fourth-generation... 

The facile conjugation of TCAS suggests the possibility of application of the diverse reporter functions of TCAS complexes, such as catalysis, energy transfer luminescence, and relaxivity, to bioanalysis and bioimaging. In combination with other components, TCAS thus provides supramolecular sensing functions, which rely on the multifunctionality of thiacalixarene. 

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