Biochip platform

Wick, 1., and Hardiman, G. (2005) Biochip platforms as functional genomics tools for drug discovery. Curr. Opin. Drug Discov. Dev. 8,347-354. 

In the context of developing practical approaches for exploiting plasmonic enhancement of fluorescence on biochip platforms, the key achievements of the work reported here are... 

Steel A., Torres M., Hartwell J., Yu Y., Ting N., Hoke G., Yang H. The Flow-Thru Chip a three-dimensional biochip platform. In Microarray Biochip Technology, M. Schena, ed. Natwick,... 

T. Basarsky, Overview of a microarray scanner design essentials for an integrated acquisition and analysis platform, in Microarray Biochip Technology (M. Schena, ed.), p. 265, Eaton Publishing (2000). 

Bayesian regularization 733 BDD 213 Beers e279 (Bio)composites 145 Biosensor calibration el73 Bioavailability 28, 47 Biochips 925 Biocomposite 358, 452 platforms 479... 

Fig. 1. A high-throughput platform of the carbohydrate-based microarrays. A high-precision robot designed to produce cDNA microarrays was utilized to spot carbohydrate antigens onto a chemically modified glass slide. The microspotting capacity of this system is approximately 20,000 spots per chip. The antibody-stained slides were then scanned for fluorescent signals with a Biochip Scanner that was developed for cDNA microarrays. The microarray results were subsequently confirmed by at least one of the conventional alternative assays.

In the microarray industry, the most commonly used techniques to pattern biologically active molecules are robotic contact printing or ink-jet printing. In general, these methods can fabricate biochips with thousands of different compounds, which can be analyzed simultaneously. The most commonly spotted biomolecules include oligonucleotides,1 proteins,2 and carbohydrates.3 Microarray-based platforms have... 

Beads in microfluidic systems are an interesting evolution of the homogeneous phase bead biochips. Indeed, examples of microfluidic platforms in which biospecific molecules are immobilized on an internal channel surface are still rare [26]. 

Manning, M., Harvey, S., Galvin, P. and Redmond, G. (2003). A versatile multi-platform biochip surface attachment chemistry. Mater. Sci. Eng. C... 

Du W, Xu Z, Ma X, Song L, Schneider EM. Biochip as a potential platform of serological interferon alpha2b antibody assay. J Biotechnol 2003 106 87-100. 

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