Bioactive saponins bioactivity

Yoshikawa, M., Murakami, T., Ueno, T., Yashiro, K., Hirokawa, N., Murakami, N., Yamahara, J., Matsuda, H., Saijoh, R., and Tanaka, O. (1997b). Bioactive saponins and glycosides. Vlll. Notoginseng (1) New dammarane-type triterpene oligoglycosides, Notoginsenosides-A, -B, -C, and -D, from the dried root of Panax notoginseng (Burk.) F. H. Chen. Chem. Pharm. Bull. 45,1039-1045. 

Yoshikawa M, Murakami T, Ueno T, Kadoya M, Matsuda H, Yamahara J, Murakami N. (1995) Bioactive saponins and glycosides, i. senegae radix. (1) E-senegasaponins a and b and z-senegasaponins a and b, their inhibitory effect on alcohol absorption and hypoglycemic activity. Chem Pharm Bull 43 2115-2122. 

CS021 Murakami, T., J. Nakamura, H. Mat-suda and M. Yoshikawa. Bioactive saponins and glycosides. XV. Saponin constituents with gastroprotective effect from the seeds of tea plant, Camellia sinensis L. var. assamica Pierre, cultivated in Sri Lanka structures of assamsaponins A, B, C, D and E. Chem Pharm Bull 1999 47(12) 1759-1764. 

From A. membranaceous, Wang [145] obtained a saponin-enriched extract and studied its effect on the isolated heart of rats. At doses of more than 50 ftg/ml, the extract showed a positive inotropic effect, which turned negative at 30 p.g/ml. The mechanism was similar to that of cardiotonic glycosides. By bioactivity-guided fractionation, the active constituent with positive inotropic activity was isolated and characterized as astragaloside IV [146]. 

Previously included, at least in part, in the Liliaceae or Amarylli-daceae, the Agavaceac, familiar plants in arid America, are known for (heir content of steroidal saponins which have been used for conversion to bioactive steroids of medicinal importance. It is... 

From different species of this genus triterpenoid saponins have been isolated, together with other compounds such as lignans, coumarins, flavonoids and polyacetylenes. The saikosaponins from Bupleurum L. are considered as the major bioactive components mainly used for their antiinflammatory and antihepatotoxic actmties. 

The saponins were isolated by bioactivity-guided fractionation of the ethanolic extract of the starfish using the brine shrimp Artemia salina L.)... 

Piacente, S. Pizza, C. Oleszek, W., Saponins and phenolics of Yucca schidigera Roezl Chemistry and bioactivity, Phytochem. Rev., 2005, 4, 177-190. 

Saponins are distributed widely in plants, including many signihcant foodstuffs and medicinal plants. In traditional Chinese herbal medicine, saponin components are of special importance many of tliem exhibit various interesting bioactivities. However, research on saponins has been limited to the isolation of these compounds and the determination of their structure. Pharmacological evaluation of saponins has been mainly retained at the folkloric level. The difficulty in isolation of saponins from... 

As expected due to chemical instability the number of acyclic peroxides is lower. Most of them occur as plant derived products, but also in soft corals hke Clavularia inflata, hydroperoxides with potent cytotoxicity exist. Interestingly the bioactivity disappeared when the hydroperoxide function was deleted. It must be noted that most of natural hydroperoxides in plants are foimd in the group of saponins from Panax ginseng or Ficus microcarpa, which are used in ethnomedicine in South East Asia. 

Yang C-R, Li X-C (1996) Bioactive Triterpenoid and Steroid Saponins from Medicinal Plants in Southwest China. Adv Exp Med Biol 404 225... 

Da Silva BP, De Sousa AC, Silva GM, Mendes TP, Parente JP (2002) A New Bioactive Steroidal Saponin from Agave attenuata. Z Naturforsch 57c 423... 

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