Senegae radix

Yoshikawa M, Murakami T, Ueno T, Kadoya M, Matsuda H, Yamahara J, Murakami N. (1995) Bioactive saponins and glycosides, i. senegae radix. (1) E-senegasaponins a and b and z-senegasaponins a and b, their inhibitory effect on alcohol absorption and hypoglycemic activity. Chem Pharm Bull 43 2115-2122. 

SENEGA Sene M rad.ix (Polygalae radix) is the dried root and rhizome of Polj ala senega var. senega and/or var. latifolia Torrey et A. Gray, family Pol alaceae. These plants grow in Southern Canada and the Middle United States, in the Mississippi region. Nowadays it is also cultivated in Japan. 

Fig. I Senegae radix Polygalae radix Milkworl root Polygala senega L. or Polygala senega var. lalifolia TORR et GREY Polygalaceae DAB 9, OAB, BP 88 ...

Fig. 1 This solvent system and the AS reagent are suitable for the separation and the detection of triterpene-saponins, e.g. senegins in Senegae radix (1), as well as steroid (ester) saponins, e.g. Smilax saponins in Sarsaparillae radix (2).

A Senegae radix (1) is characterized by four to five red saponin zones (R, 0.2-0.4) with senegin II as the major compound at R, — 0.2. 

Yoshikawa, M., T. Murakami, H. Matsuda, et al. 1996. Bioactive saponins and glycosides. II. Senegae Radix. 2) Chemical stmc-tures, hypoglycemic activity, and ethanol absorption-inhibitory effect of E-senegasaponin c, Z-senegasaponin c, and Z-senegins II, III, and IV. Chem. Pharm. Bull. 44(7) 1305-1313. 

Yoshikawa, M., T. Murakami, T. Ueno, et al. 1995. E-Senegasaponins A and B, Z-senegasaponins A and B, Z-senegins II and III, new type inhibitors of ethanol absorption in rats from Senegae Radix, the roots of Polygala senega L. var. latifolia Torrey et Gray. Chem. Pharm. Bull. 43(2) 350-352. 

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