Ficus microcarpa

As expected due to chemical instability the number of acyclic peroxides is lower. Most of them occur as plant derived products, but also in soft corals hke Clavularia inflata, hydroperoxides with potent cytotoxicity exist. Interestingly the bioactivity disappeared when the hydroperoxide function was deleted. It must be noted that most of natural hydroperoxides in plants are foimd in the group of saponins from Panax ginseng or Ficus microcarpa, which are used in ethnomedicine in South East Asia. 

Nomofungin (81), which had a pyran oxygen instead of an NH in 71, was isolated from the fermentation broth of an unidentified endophytic fungus obtained from the bark of Ficus microcarpa [52]. Later synthetic studies of nomofungin revealed that this compound was identical to 71 [53,54]. 

Taxonomy Cycloartane Triterpenoids Ficus microcarpa L. f. (Moraceae) [1]. 

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