Bioactive molecule-releasing scaffolds for bone tissue engineering

2 Bioactive molecule-releasing scaffolds for bone tissue engineering [Pg.178]

Bioactive molecule Type of molecule delivered References [Pg.179]

Drug entrapment is achieved via physical interaction between the bioactive molecule and the carrier system usually by attachment to the matrix surface, by entrapment within it by the aim of a covalent binding, or by drug preencapsulation. Table 8.2 lists general basic approaches for drug encapsulation into 3D PNC scaffolds for BTE. [Pg.179]

In all cases, entrapment efficiency will be determined by the affinity of molecular interactions bnt also will be influenced by the environments in terms of pH and ionic strength. In addition, understanding the efforts to increase drug entrapment [Pg.179]

Drug encapsulation system Main characteristics of the system Drug encapsulation efficiency Predominant drug release mechanism [Pg.180]

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