Drug encapsulation efficiency

The interfacial cross-linking polymerization has been demonstrated to be a suitable method for the production of xylan microcapsules with high drug encapsulation efficiency. SD-... 

Saxena A., Sachin K, Bohidar H.B., Verma A.K. 2005. Effect of molecular weight heterogeneity on drug encapsulation efficiency of gelatin nano-particles. Colloids and Surfaces B Biointerfaces 45,42-48. 

Drug encapsulation efficiency Active or remote loading [11] Stable liposome encapsulation of drugs at high drug-to-lipid ratios, Many applications in drug delivery... 

As mentioned above, the ability to adsorb to the cornea and an optimal drug release rate have been defined as the two liposomal attributes most responsible for increasing bioavailability after topical ocular administration. A number of factors, including drug encapsulation efficiency, liposome size and charge, distribution of the drug within liposomes, stability of liposomes in the conjunctival sac and ocular tissues, their retention in the conjunctival sac, and most importantly their affinity toward the corneal surface and the rate of release of the encapsulated drug, have... 

Reithmeier investigated the influence of fat/phospholipid ratio to improve drug encapsulation efficiency into microparticles prepared by the solvent evaporation method [37], A cosolvent-solvent evaporation method like the one described above for the preparation of polymer lipospheres [35] was used. Here, somatostatin as a model peptide was dissolved in methanol and added to a solution of the lipid components in hexane [37],... 

Concentration of both polymer and cross-linking electrolyte play a major role in deciding the properties of intended hydrogel beads. Concentration of both polymer and electrolyte is calculated based on the ratio of number of cross-linking units present. Drug encapsulation efficiency of the prepared hydrogel beads depends mainly on type and concentration of electrolytes used in the process. 

Small unilamellar vesicles (SUVs) of different lipids are coated with chitosan (CHT) by dropwise addition. These CHT-coated liposomes are found to show increased drug encapsulation efficiency, nebulization efficiency, mucoadhesive property, and decrease in toxicity level of the drugs toward epithelial cells. Therefore, CHT-coated liposomes are considered to be advantageous for the drug delivery to the lungs by the method of nebulization. 

Besides high thermodynamic stability and drug encapsulation efficiency, the cellular uptake and tissue penetration of LDBC micelles for drug delivery can be tuned by surface functionalization with targeting agents and changes in surface charge. For instance, a dendron-based nanocarrier platform was developed based... 

Drug encapsulation system Main characteristics of the system Drug encapsulation efficiency Predominant drug release mechanism... 

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