BFCs Controlled by Logically Processed Biochemical Signals

3 BFCs Controlled by Logically Processed Biochemical Signals 

The above-described (see Section 18.6) polyvinylpyridine (PVP) brush functionalized with the Os(dmo-bpy)2Cl redox centers was used to generate the pH-switchable interface capable of mediating electron transport with enzymes only being in the ON state at pH 4.5 [30]. Laccase is a well-known enzyme frequently 

FIGURE 18.21 (a) The bioelectrocatalytic cathode for O2 reduction in the presence of laccase controlled hy pH. (h) The cyclic voltammograms obtained for the modified electrode in the presence of O2 at different pH values (i) 6 (ii) 4 (iii) 6. Inset Reversible changes of the electrocatalytic current in the cyclic voltammograms upon stepwise pH changes. (Adapted with permission from Ref. [41]. Copyright 2009, American Chemical Society.) 

The present developments and future expectations are based on the application of a multidisciplinary approach that will require further collaborative contribution from electrochemists, specialists in materials science and unconventional molecular and biomolecular computing. 

This work was supported by NSF (Award No. CBET-1066397) and by the Semiconductor Research Corporation (Award 2008-RJ-1839G). The authors thank all students and collaborators who made this interesting research possible. 

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