6- Benzyl-3-methyl-3-nitro

Benzyl-methyl-nitro- E16a, 1155 f. (N-Nitrier.), 1161 (NH -v N-CH3) Methyl-(4-methyl-phenyl)-nitro-E16a, 1175 (N-Nitrier.) Nitro-(l-phenyl-ethyl)- XI/2, 105 Anilin... 

Amin (4-Cyan-benzyl)-methyl-nitro-E16a. 1161 f. (N-Alkylier.) Benzoesaure 4-Azido- -ethylester X/3, 807... 

Amin (4-Dimethylamino-benzyl)-methyl-nitro- Elba, 1168... 

Amin (2-Ethoxycarbonylamino-benzyl)-methyl-nitro-E16a, 1167 (N-Aminoalkylier.)... 

The argtiments of Norman and his co-workers seem to give affirmative answers to the first and second of these questions, but it is doubtful if the available data further require such an answer for the third question. It can be argued that the crucial comparison made between the behaviour of benzyltrimethylammonium ion and protonated benzyl methyl ether is invalid, and that it is possible to interpret the results in terms of nitration by the nitronium ion, modified by protonation of the oxygen atom of the ether a case for the possible involvement of the nitro-nium ion in specific interaction leading to o-substitution has been made. ... 

Imidazolidin-2-one, l-(5-nitro-2-thiazolyl)-pharmacological activity, 6, 328 Imidazolidin-4-one, l-aryl-3-phenyl-2-thioxo- C NM S, 355 Imidazolidinones C NMR, 5, 355 Imidazolidin-2-ones nucleophilic displacement, 5, 428 polymers, 1, 279-280 reactivity, 5, 376 synthesis, 5, 466, 471 Imidazolidin-4-ones synthesis, 5, 468 Imidazoline, 2-alkyl-synthesis, 5, 463 Imidazoline, 2-amino-applications, 5, 498 Imidazoline, 2-aryl-synthesis, 5, 463 Imidazoline, 2-methyl-synthesis, 5, 487 Imidazoline, 2-nitroamino-synthesis, 5, 471 2-Imidazoline, 2-arylamino-tautomerism, 5, 368 2-Imidazoline, 1-benzyl-methylation, 5, 425 2-Imidazoline, 1,2-diaryl-synthesis, 5, 463... 

Methyl-phenyl- -S-(4-methyl-phenylester) El, 266 [ -(4-Nitro-anilino)-benzyl]-methyl- -butylester-(2-phenyl-hydrazonid) E2, 294 Pentafluorphenyl-phenyl- -chlorid E2, 253 Phenyl-1-propinyl- -S-(2-methy]-propylester)... 

Methyl-(4-methyl-benzyl)-nitro-E16a. 1161 (N-Alkylier.) Methyl-nitro-(2-phenyl-ethyl)- E16a, 1159 (NO - N02)... 

Oxazin 5-Methyl-3-(4-methyl-benzyl)-5-nitro-tetrahydro-E14a/2, 711 (l,3-Diol/CH20/ R-NH2)... 

Aromatic and aliphatic amino ethers have been synthesized by this method. An example of the formation of a cyano ether is the preparation of p-cyano benzyl methyl ether from the substituted benzyl bromide and sodium methoxide (84%). Also, certain aryloxyacetonitriles, AtOCHjCN, are made by the condensation of chloroacetonitrile with sodium phenoxides in a solution of methyl ethyl ketone containing a small amount of sodium iodide (70-80%). Aromatic nitro ethers, like o- and p-nitrodiphenyl ether, have been prepared by the Ullmann procedure (84%). The synthesis of alkyl p-nitrophenyl ethers has also been accomplished with good yields (55-92%). ... 

In addition, manganese oxide oxidizes benzylic methyl or methylene to carbonyl [814] and cleaves the carbon bonds of vicinal diols [577, 522]. It converts amines into imines [577, 525] tertiary amines into secondary amines [572], formamides [526, 527, 525], or ketones aromatic primary amines [575, 525] and hydrazo compounds [525] into azo compounds hy-droxylamines into nitroso [576] or nitro compounds [525] hydrazones into diazo compounds [520] phosphines into phosphine oxides [575] thiols into disulfides [576] and sulfides into sulfoxides [541]. 

Bcnzylamino-5-brom- 240 2-Benzylamino-5-hydroxy-4-phenyl- 160 5-Bcnzylainino-4-methoxycarbonyl- 149 2-Benzylamino-4-methyl- 93 2-Benzylamino-5-nitro-4-phenyl- 136 2-Benzylamino-5-phenylthio- 293 4-Benzyl-2-(benzyl-methyl-amino)- 228 4-Benzyl-2-(bcnzyl-mcthyl-amino)-5-formyl-... 

Benzyl- 571, 582, 591 l-Benzyl-4-brom- 577 l-Benzyl-3,4-dibrom- 577 l-Benzyl-5-halogen-4-nitro- 702 l-Benzyl-3-methyl- 577, 651 l-Benzyl-5-methyl- 577 l-Benzyl-5-nitro- 591 l-Benzyl-3,4,5-tribrom- 577 4,5-Dimethyl-l-hydroxy-3-phenyl- 408... 

Methoxycarbonyl-benzyl)-6-nitro- 825 7-Methoxycarbonyl- i -phenyl- 800 3-Methoxycarbonyl-4,5,6,7-tetraphenyl- 812 1 -(Mcthoxy-methyl)-6-nitro-... 

Benzyl-[2-nitro-benzyl]-amin 18. 1078. Methyl-ghenyl-[3-nitro-benzyl]-8min... 

Drop 1 g. of sodium into 10 ml. of ethyl alcohol in a small flask provided with a small water condenser heat the mixture until all the sodium has dissolved. Cool, and add 1 g. of the ester and 0-5 ml. of water. Frequently the sodium salt of the acid will be deposited either at once or after boiling for a few minutes. If this occurs, filter oflF the solid at once, wash it with a little absolute ethyl alcohol (or absolute methylated spirit), and convert it into the p-bromophenacyl ester, p-nitro-benzyl ester or S-benzyl-tso-thiuronium salt (for experimental details, see Section 111,85). If no solid separates, continue the boiling for 30-60 minutes, boil oflF the alcohol, allow to cool, render the product just neutral to phenolphthalein with dilute sulphuric or hydrochloric acid, convert the sodium salt present in solution into a crystalline derivative (Section 111,85), and determine its melting point. 

Tertiary, benzyl, and aHyhc nitro compounds can also be used as Friedel-Crafts alkylating agents eg, reaction of (CH2)3CN02 (2-nitro-2-methyl propane [594-70-7]) with anisole in the presence of SnCl gives 4-/-butylanisole [5396-38-3] (7). SoHd acids, such as perfluorodecanesulfonic acid [335-77-3], and perfluorooctanesulfonic acid [1763-23-1] have been used as catalysts for regio-selective alkylations (8). 

Benzyl saUcylate can be prepared by the reaction of ben2yl chloride with an alkaU salt of saUcyhc acid at 130—140°C or by the transesterification of methyl saUcylate with benzyl alcohol. It is used as a fixative and solvent for nitro musks and as a fragrance for detergents. Benzyl saUcylate was priced at... 

Theophylline, 9-aryl-synthesis, 5, 576 Theophylline, 8-arylamino-synthesis, 5, 576 Theophylline, 9-benzyl-rearrangement, 5, 534 Theophylline, 8-chloro-reduction, 5, 541 Theophylline, 6-deoxy-reduction, 5, 541 Theophylline, 8-dimethylamino-synthesis, 5, 580 Theophylline, 8-methyl-synthesis, 5, 591 Theophylline, 8-methylthio-synthesis, 5, 578 Theophylline, 8-nitro-synthesis, 5, 538 Theophylline, 7-phenyl-synthesis, 5, 581 Theophylline, 8-phenyl-7-oxide... 

The cleavage proceeds by initial reduction of the nitro groups followed by acid-catalyzed cleavage. The DNB group can be cleaved in the presence of allyl, benzyl, tetrahydropyranyl, methoxy ethoxy methyl, methoxymethyl, silyl, trityl, and ketal protective groups. 

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