3-benzoyloxy-2-methyl

Performing a Vilsmeier-Haack reaction on 3-benzoyloxy-2-methyl-quinazolin-4-one (184) afforded the isoxazolo[3,2- ]quinazolinone (185) [86IJC(B)709]. This ring system (187) was also synthesized by cyclocondensation of anthranilic acids or isatoic anhydrides with the isoxazolin-3-ones (186) (77AF766 83MIP1), or by condensation of methyl anthrani-late with 3-chloropropanoyl chloride followed by cyclization with hydroxylamine hydrochloride (77AF766). 

P-Cocaine 2P-carbomethoxy-3-p-benzoxytropane, methyl [lR-(cjro,exo)]-3-(benzoyloxy)-2-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate [50-36-2] M 303.4, m 98°, b 187-188°/0.1mm, [a]p -15.8° (c 4, CHCI3), pK 8.39. Crystallises from EtOH and sublimes below 90° in a vacuum in a non-crystalline form. 

Danishefsky and coworkers employed two hetero Diels-Alder reactions in a total synthesis of the ansa bridge of rifamycin S (Scheme 52) The first cyclocondensation reaction uses the trimethylsilyloxy diene (14) and a preincubated solution of 3-(benzoyloxy)-2-methyl-1-propanal (188) with an excess of TiCU in CHCh. The product is exclusively the syn-ACF pyrone (189). Through a Ferrier rearrangement and a sequence of oxidation-reduction steps followed by functional group manipulations aldehyde (190) is obtained. 

When 6-hydroxychromans act as antioxidants, they are themselves oxidized to one or more of several compounds depending on the conditions. Amongst the commonest products from a-tocopherol are a-tocopherylquinone (702), a-tocored (703), the 5-benzoyloxy-methyl derivative (704) and the spiro dimer (705). 

Butane 2-(Benzoyloxy-methyl)-l,4-dibenzyloxy-2-fluoro- ElOb,. 92 (OH - F)... 

Acetoxy-methyl)-phenyl- Ell, 873 (Pummerer-Reaktion) (Benzoyloxy-methyl)-methyl- Ell, 873 (Pummerer-Reaktion)... 

Beilstein Handbook Reference) Benzoflex S-552 Benzoic acid, tetraester with pentaerythritol 2,2-Bis((benzoyloxy)methyl)-1,3-propane-diol dibenzoate BRN 3513249 CCRIS 5971 EINECS 224-079-8 NSC 166502 Pentaerythritol tetrabenzoate 1,3-Propanediol, 2,2-bis( benzoyloxy)methyl)-, dibenz-oate Uniplex 552. Plasticizer for adhesives intended for heat seal applications Solid mp = 102-104°. Unitex. 

Bis ((benzoyloxy) methyl)-1,3-propanediol, dibenzoate. See Pentaerythrityl tetrabenzoate... 

A -Benzoylornithine, in 0-10049 8a-Benzoyloxyacetylpringleine, in H-10025 l-[(Benzoyloxy)methyl]-7-oxabicyclo[4.1.0] hept-3-ene-2,5-diol 5-benzoate, see P-30113... 

Benzoyloxy) methyl]-3,8-dioxatricy-clo[5.1.0. w ]octane-5,6-diol diacetate,... 

Dianhydro-2-C-[(benzoyloxy)methyl]-D-c/)i-inositol diacetate, C-156 Dianose, D-607 Dianthoside, H-178 Diarabinopyranosylamine, D-517... 

An enantioselective synthesis of carbocyclic tetrazole C-ribonucleosides has been accomplished by first preparing the intermediate (lS,2S,3R,4R)-4-benzoyloxy-methyl-2,3-isopropylidenedioxycyclopentene-l-carbonitrile 1417 from its carboxamide 1416 by dehydration with TFAA in 97% yield. Cyclization of 1417 with azide then gives the tetrazole 1418 [1079]. 

Typical procedure. 3-(BenzoYloxY)-3-[(benzoYloxY)methYl]cYclohexane-1,2-dione 1878 [1398] Trifluoroacetic anhydride (104 pL, 155 mg, 0.74 mmol) was added over 5 min to a solution of dimethyl sulfoxide (70 pL, 77 mg, 0.99 mmol) in dry dichloromethane (1.1 mL) at 70 °C under argon. After stirring for 20 min at —70 °C, 2-(benzoyloxy)-2-[(benzoyloxy)methyl]-6-hydroxycyclohexane (192 mg, 0.5 mmol) was added over 5-10 min, and stirring was continued for a further 30 min. Triethylamine (20 pL, 15 mg, 0.1 mmol) was then added over 10-15 min, the solution was allowed to warm to room temperature, and water was added. The mixture was extracted with diethyl ether, and the combined extracts were washed with 5% aq. hydrochloric acid and water, dried over sodium sulfate, and concentrated under reduced pressure. The residue was chromatographed on silica gel (100-200 mesh, 15 g) eluting with 10% ethyl acetate/hexane to give the product, which was crystallized from methanol yield 125 mg (0.34 mmol, 68%) of 1878. 

Trimethyl- [/ -benzoyloxy- - methyl-bufyl]-ammoniumbydrozyd 9,176. Cedrenketosaure-ozim 10, 652. Bem8teuiB are[Pg.1005]

C,aH I(a0a Iir-[i3-(3-Nitro-benzoyloxy)- methyl-butyl]-piperazin.N -carbon< siure-athyleeter 23 II9. 

Amino-benzoyloxy ] -methyl-piperidin-carbons ure-(3) tliyleeter 82 II144. 

Ca. 3.3 moles triethylamine added at -5 to a stirred suspension of 2-benzoyloxy-methylbenzoic acid and glycinamide hydrochloride in pyridine, then ca. 0.66 mole PClj added dropwise below 0°, and stirred 24 hrs. at 0° 2-[2-(benzoyloxy-methyl)benzamido]acetamide. Y 78%. F. e. s. B. F. Cain, J. Org. Chem. 41, 2029 (1976). 

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