Benzoic 3,4,5-trihydroxy

As can be expected, the high-temperature processing runs the risk of enhancing side and consecutive reactions. Decarboxylation of the main product was found and increases with temperature (see Fig. 7). This is illustrated at the example of the synthesis of 2,4,6-trihydroxy benzoic acid from phloroglucinol, as this molecule is even more sensitive to thermal destruction due to the enhanced electron richness of the aromatic core by presence of a third hydroxyl group (Hessel et al. 2007). 

Metbylene Blue 2,2 -Methylenebis[3,4,5-trihydroxy-benzoic acid]... 

LiChrosorb RP-8 UV280 nm MeOH/10 mM Phosphate buffer (40/60) Benzoic acid, Pyrogallol, Trihydroxy -benzophenone 37... 

GALLIC ACID Gallic Add Monohydrate, 3,4,5-Trihydroxy-benzoic Add NL 0 1 0... 

Benzimidazole derivatives, III, 161 Benzimidazole rule of rotation, I, 21 1,3-Benzodioxan, 8,8 -methyIenebis(6- nitro-), III, xvii Benzoic acid, cellulose esters, I, 320 labelled with isotopic C, III, 231 starch esters, I, 302, 303 —, 2,4-dihydroxy-, effect on conductivity of boric acid, IV, 195 —, 2,4,5-trihydroxy-, effect on conductivity of boric acid, IV, 195 —, 3,4,5-trihydroxy-. See Gallic acid. 

More recently benzoic acid derivatives (MW 122-170) have also been shown to be astringent (17). The most astringent compounds, salicylic (2-hydroxy benzoic acid) and gentisic (2,5 dihydroxy benzoic acid) acids, were ortho substituted, but neither had vicinal hydroxyl groups. Both derivatives had lower pHs than the non-ortho substituted ones, which may have contributed not only to sourness but also to astringency. McManus et al (1981) (18) proposed previously that simple phenols which contain 1,2 dihydroxy or 1,2,3 trihydroxy groups (such as epicatechin or catechin) may cross link and thereby precipitate proteins. It could be speculated that ortho substitution conveys some kind of binding capability similar to that of flavan-3-ols or polyphenolics of hi er MW. 

TRIHYDROXYBENZOIC ACID PROPYL GALLATE n-PROPYL-3,4,5-TRIHYDROXYBENZOATE TEXOX PG 3,4,5-TRim DROXYBENZENE-l-PROPYLCARBOXYLATE 3,4,5-TRIHYDROXY-BENZOIC ACID, n-PROPYL ESTER... 

Ethyl 4-hydroxy[1-13C]benzoate can be converted into other ring-13C-labeled compounds like 3,4-dihydroxy[1-13C]benzoic acid, 1,3,4-trihydroxy[1-13C]benzene, and D,L-[1 -13C]tyrosine.4b... 

TMBA, a drug intermediate widely used for an antibiotic Trimethoprim, has been traditionally made from gallic acid (3,4,5-trihydroxy benzoic acid) or vanillin imported from China where they extract it from a particular bark of a tree. However, during the last decade or so, it has been more economically made from p-cresol... 

Gallic Acid Gallic Acid Monohydrate 3,4, 5-Trihydroxy-Benzoic Acid ... 

H.75) Benzoic acid, 3,4,5-trihydroxy-, 3,4,5-trihydroxybenzoic acid, gallic acid [149-91 -7]... 

Zorubicin. Benzoic acid I-[4- (3-amino-2,3,6-trideoxy-a -L-lyxo-hexopytanosyiloxy]-l,2,3,4,6,11-hexahy-dro-2, S, 12-trihydroxy-7-methoxy.6,l l-dioxo-2-napthacen-yl]ethylidene]hydrazide benzoic acid hydrazide 3-hydrazone with daunorubicin RP 22,050, C H NjO, mnl wt 645.67. C 63.25%, H 5,46%, N 6.51%, O 24.78%. Semi-synthetic antibiotic related to daunoruhicln, q.v. Prepn G. Jnlles,... 

Beilstein Handbook Reference) AI3-00861 Benzoic acid, 3,4,5-trihydroxy-, methyl ester BRN 2113180 CCRIS 5567 EINECS 202-741-7 Gallic acid methyl ester Methyl 3,4,5-trihydroxybenzoate Methyl gallate Methylgallate NSC 363001. Used by ophthalmologists as an antiseptic in conjunctivifis. Crystals mp = 202 soluble in hot H2O, EtOH, MeOH, Et20. 

Anand K K, Singh B, Saxena A K, et al. (1997). 3,4,5-trihydroxy benzoic acid (gallic acid), the hepatoprotective principle in the fruits of Terminalia belerica-hioassay guided activity. Pharmacol. Res. 36 315-321. 

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