Benzene cyclohexyl

When cyclohexene is mixed with anhydrous triflic acid under a high pressure of carbon monoxide (120 atm) followed by the addition of benzene, cyclohexyl phenyl ketone and the isomeric cyclohexenyl cyclohexyl ketones are obtained with little isomerization of the initially formed cyclohexyl cation 22 to methylcyclopentyl cation 23 (Scheme 5.46).422... 

OTHER COMMENTS used as a solvent for cellulose ethers, fats, oils, waxes, bitumens, resins, lacquers, and crude rubber paint and varnish remover used in the manufacture of adipic acid, benzene, cyclohexyl chloride, nitrocyclohexane, cyclohexanol, and cyclohexanone useful in the manufacture of nylon and solid fuels may also be used in the industrial recrystalli-zation of steroids. 

Write a reasonable mechanism for the formation of cyclohexyl benzene from the reaction of benzene cyclohexene and sulfuric acid J... 

A variety of 2,5-dialkylfurans are available via the Paal-Knorr condensation cyclization is possible for both hindered and unhindered 1,4-diketones. Fleming prepared 2-cyclohexyl-5-methylfuran (31) in 91% yield via treatment of dione 30 with catalytic p-toluenesulfonic acid in refluxing benzene. Using the same methodology, Denisenko synthesized furan 33 in 35% yield from the corresponding dione (32). ... 

The reaction mixture is cooled and 50 grams of ammonium chloride dissolved in 200 cc of water is added dropwise thereto with stirring. The decomposed Grignard complex is then filtered. Benzene is added to the ether filtrate and the solvents are removed therefrom on a steam bath. The residue is fractionated and the base, N-((3-cyclohexyl- 3-hydroxy- 3-phenyl-ethyl)N -methylpiperazine, is obtained as a liquid having a boiling point of 196° to 203°C at a pressure of 4.0 mm. 

Benzene, propyl acetate, allyl acetate, 1-pentanol, cyclohexanone, cyclohexanol, dicyclohexyl ether, cyclohexyl valerate, butyric acid, valeric acid, caproic acid, 1,5-pentanediol, dicyclohexyl succinate, and dicyclohexyl glutarate 30 m DB-FFAP column, 60-200° at 67min. 

If one limits the consideration to only that limited number of reactions which clearly belong to the category of nucleophilic aromatic substitutions presently under discussion, only a few experimental observations are pertinent. Bunnett and Bernasconi30 and Hart and Bourns40 have studied the deuterium solvent isotope effect and its dependence on hydroxide ion concentration for the reaction of 2,4-dinitrophenyl phenyl ether with piperidine in dioxan-water. In both studies it was found that the solvent isotope effect decreased with increasing concentration of hydroxide ion, and Hart and Bourns were able to estimate that fc 1/ for conversion of intermediate to product was approximately 1.8. Also, Pietra and Vitali41 have reported that in the reaction of piperidine with cyclohexyl 2,4-dinitrophenyl ether in benzene, the reaction becomes 1.5 times slower on substitution of the N-deuteriated amine at the highest amine concentration studied. 

Finally, reaction of primary, secondary, or tertiary alcohols 11 with Me3SiCl 14 in the presence of equivalent amounts of DMSO leads via 789 and 790 to the chloro compounds 791 [13]. n-Pentanol, benzyl alcohol, yS-phenylefhanol or tert-butanol are readily converted, after 10 min reaction time, into their chloro compounds, in 89-95% yield, yet cyclohexanol affords after reflux for 4 h cyclohexyl chloride 784 in only 6% yield [13] (Scheme 6.5). 1,4-Butanediol is cyclized to tetrahydrofuran (THF) [13a], whereas other primary alcohols are converted in 90-95% yield into formaldehyde acetals on heating with TCS 14 and DMSO in benzene [13b] (cf also the preparation of formaldehyde di(n-butyl)acetal 1280 in Section 8.2.1). 

Benzoyl hydroperoxide was used for the conversion of divinyl sulphide into divinyl sulphoxide by Levin as early as 1930. In 1954 Bateman and Hargrave reported that saturated sulphides may be oxidized to sulphoxides by means of cyclohexyl or t-butyl hydroperoxide. These authors found that in both polar and non-polar solvents oxygen transfer occurred to give quantitative yields of sulphoxides over a wide range of experimental conditions according to equation 7. It was also reported that a quantitative yield of sulphoxides was obtained from the reaction of unsaturated sulphides with t-butyl and cyclohexyl hydroperoxides in methanol. With t-butyl hydroperoxide in benzene the sulphoxide yield was in no case stoichiometric, varying from 90 to 5% under the condition chosen. 

Phenylnaphthalene has been prepared by the reaction of a-halonaphthalenes with mercury diphenyl3 6 or with benzene in the presence of aluminum chloride,6 and by means of the Gri-gnard synthesis, starting with either bromobenzene, cyclohexyl chloride, and a-tetralone 7 or with a-bromonaphthalene and cyclohexanone.6 8 9 Dehydrogenation of the reduced naphthalene has been accomplished by the use of sulfur,6 bromine,8 platinum black, or selenium.7 The formation of the hydrocar-... 

The reduction of hydroxylamine by titanous salts in water produces the free amino radical, a reaction analogous to the formation of triphenylmethyl from the carbinol and a reducing agent.138 The amino radical will attack benzene to give diaminocyclohexadiene and di-(aminocyclohexadienyl) it converts cyclohexene into cyclohexyl-amine.139... 

METHYL]SULFONYL]BENZENE AND (Z)-[2-(FLUOROMETHYLENE)CYCLOHEXYL] BENZENE... 

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