Benign prostatic hyperplasia prostatectomy

Unless the sphincter mechanism is compromised by surgery or trauma, SUI is exceedingly rare in males. The most common surgeries predisposing to SUI in males are radical prostatectomy for prostate cancer and transurethral resection of the prostate for benign prostatic hyperplasia. 

Benign prostatic hyperplasia (BPH) (Prascar on/yj.Treatment of symptomatic BPH in men with an enlarged prostate to improve symptoms, reduce acute urinary retention risk, and reduce the risk of the need for surgery including transurethral resection of the prostate (TURP) and prostatectomy. 

The first study where the SCS was applied to MRS analysis of prostate biopsies was undertaken at the IBD in Winnipeg.42 Proton MRS (Bruker Instruments, 8.5 T were performed at 37°C on specimens of benign (n = 66) and malignant (n = 21) human prostate tissue specimens collected from transurethral resection of the prostate and radical prostatectomy from 50 patients. Typical spectra of malignant prostate tissue and benign prostate hyperplasia (BPH) are shown in Fig. 5.42 The spectral data were subjected to visual inspection analysis and multivariate analysis, specifically LDA. 

A woman, who was a neighbor, had a champion show dog with severe benign prostatic hyperplasia. Her veterinarian suggested a prostatectomy for this chronic condition. This was unacceptable, as the dog s owner received substantial income from the dog s stud fee. The dog was given saw palmetto and vitamin E, which reduced the symptoms and the need for surgery. Over the next few years the dog sired many more puppies."... 

In men, SUI is most commonly the result of prior lower urinary tract surgery or injury, with resulting compromise of the sphincter mechanism within and external to the urethra. Radical prostatectomy for treatment of adenocarcinoma of the prostate is probably the most common setting in which surgical manipulation leads to UI. Overall, SUI in the male is uncommon, and in the absence of prior prostate surgery, severe trauma, or neurologic illness, is extraordinarily rare. Transurethral resection of the prostate for benign prostatic hyperplasia (see Chap. 82) may also lead to SUI in men. 

Figure 8 500 MHz H NMR magic angle spinning spectra of prostatic tissue from humans with malignant prostate cancer sampled by transurethral radical prostatectomy (TURP) (A), or needle biopsies (B, C) contrasted with that of a benign prostatic hyperplasia (BPH) patient sampled via radical prostatectomy (D). Spectrum (C) is different, as the needle has sampled a different region of the prostate. The spectrum of the prostate tissue from the BPH patient (D) displays higher levels of citrate but lower lipid levels relative to spectra (A) and (C) from the malignant cancer patients. (See Tomlins AM, Foxall PJD, Lindon JC, Lynch MJ, Spraul M, Everett JR, and Nicholson JK (1998). Analytical Communications 35 113-115).

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