Behavior and tremor

Acute inhalation of diesel fuel no. 2 vapor induced dose-dependent ataxia, increased sensitivity to heat, changes in behavior, and tremors in mice. Also, while ataxia occurred, there was no affect on the spinal... 

Hydrazine is absorbed through the skin. In one case attributed to hydrazine hydrate exposure, systemic effects included weakness, vomiting, excited behavior, and tremors the chief histologic findings were severe tracheitis and bronchitis, fatty degeneration of the liver, and nephritis. ... 

McCarron s paper (this volume) describes the behaviors of 1,000 adults admitted to an inpatient service with acute symptoms of PCP intoxication. She states that some of the patients have appropriate behavior while many have mute and staring episodes, bizarre facial grimacing, localized dystonic reactions, rigidity, tremors, coarse jerky movements, and nystagmus. Thus, there is similarity between the acutely intoxicated adult s behavior and that of the newborn with a positive urine toxic screen for PCP. 

Some information is available to identify neurological effects in humans from inhalation exposures. The available data indicate that coordination and concentration difficulties, headache, intoxication, and/or anorexia may be induced by inhalation of JP-5 vapor (Porter 1990), headaches may be induced by diesel fuel vapor (Reidenberg et al. 1964), and sensory impairment may be induced by deodorized kerosene vapor (Carpenter et al. 1976). In animals, a few studies were found that document neurological effects from inhalation of fuel oils. Acute inhalation of diesel fuel no. 2 vapor produced behavioral changes, tremors, ataxia, reduced coordination, and increased sensitivity to heat in mice (Kainz and White 1984). 

Alcoholism is among the major health problems in most countries. Dependence on ethanol, as with other addictive drugs, is expressed as drug-seeking behavior and is associated with a withdrawal syndrome that occurs after abrupt cessation of drinking. The ethanol withdrawal syndrome is characterized by tremors, seizures, hyperthermia, hallucinations, and autonomic hyperactivity. 

Lewis Carroll s fictional Mad Hatter could well have been based upon some real people. In those days the felt used for hatmaking was made from rabbit, hare, or beaver fur, which the hatter would mat by treating it with hot mercuric nitrate. Erratic behavior, along with swollen gums and tremors, became the recognized consequences of hatting. 

Repeated GHB use is associated with mood swings, liver tumors, violent behavior, and dependence. If the drug is discontinued, the user can experience withdrawal. Severe withdrawal symptoms include extreme agitation, delirium, insomnia, tremor, rapid heart rate, and anxiety. 

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