Bacopa

Shukla, O.P., Dubey, S., and Rai, U.N., Preferential accumulation of cadmium and chromium Toxicity in Bacopa monnieri L. under mixed metal treatments, Bulletin of Environmental Contamination and Toxicology, 78, 252-257, 2007. 

T. Renukappa, G. Roos, I. Klaiber, B. Vogler, and W. Kraus, Application of high-performance liquid chromatography coupled to nuclear magnetic resonance spectrometry, mass spectrometry and bioassay for the determination of active saponins from Bacopa Monniera Wettst.,7. Chromatogr. A 847 (1999), 109-116. 

Bacopa monnieri (Brahmi) is a very significant plant of Ayurved. The inoculation studies were carried out at the Surjeevan Farma. The plants were inoculated with the mycorrhiza inoculum by putting 1.5 g of the inoculum 2 deep round the root zone during the 1st week of July and allowed to grow for three months. 

Bacopa monneria has been shown in recent studies to stimulate hair growth in laboratory mice. Traditionally, this Ayurvedic herb, known as brahmi, was used to increase hair growth, stimulate cerebral circulation, and treat impaired memory and poor concentration. 

Source Bacopa monneira. Biological activity Nootropic. 

Jain P, Kulshreshtha DK. Bacoside Al, a minor saponin from Bacopa monniera. Phytochemistry 1993 33 449-451. 

S. Bacopa monnieri L. Bramia monnieri L. Herpestts monniera H. B. et K. Scrophulariaceae Ind, Pak, Mai, Phi, Sri whole plant root stalk leaves whole plant epilepsy epilepsy < nocturnal epilepsy +AUD +FTZ -MES fraction aqueous ext. 95% ethanolic ext. 50, 52, 64 34, 36, 37 65 66... 

Bacopa monniera Wettst, popularly known as Brahmi is widely used as a nervine tonic for memory improvement, cardio tonic and diuretic in Indian traditional medicine [63]. The alcoholic leaf extract of the plant was reported to improve the performance of rats in various learning experiments as manifested by better acquisition, consolidation and retention of newly acquired behavioural responses [64-66]. The activities... 

As a general rule, Bacopa monnieri is brahmi in Kerala and mandukaparni in north and west India, whereas Centella asiat-ica is called brahmi in north and west India and mandukaparni in Kerala (south India) (McGuffin et al. 2000). 

Human dose escalation and safety studies have indicated that bacopa is generally well tolerated, with only minor and transient adverse events, primarily gastrointestinal discomfort, reported (Pravina et al. 2007 Singh and Dhawan 1997). 

An animal study with large doses (250 mg/kg) of bacopa demonstrated a decrease in sperm count and viability. All parameters were shown to return to normal several weeks after cessation of treatment (Singh and Singh 2009). No human studies on the safety or efficacy of bacopa as a male contraceptive have been completed. 

No information on the safety of bacopa in pregnancy or lactation was identified in the scientific or traditional literature. Although this review did not identify any concerns for use while pregnant or nursing, safety has not been conclusively established. 

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