Azure

CA Index Name Phenothiazin-5-ium, 3-ainino-7-(di-methylamino)-, chloride (1 1) 

Other Names Azure A Phenothiazin-5-ium, 3-amino-7-(dimeihylamino), chloride 3-Amino-7-(dimethylami-no)phenazaihionium chloride 5-Chloro-3-dimethylami-no-7-amino-5//-phenothiazine Azur A Azurea dye C.I. 52005 A,A-Dimeihylihionine 

Merck Index Number 927 Chemical/Dye Class Phenothiazine Molecular Formula C14H14CIN3S 

Physical Form Dark green powder or crystals 

Solubility Soluble in water, methanol, glycerol sparingly soluble in ethanol Melting Point 290 °C (decompose) 

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Bui Iheri are on the Azur coast, Kotl in mHnv otVi -.i Jisiriols it imporiani rose hardens, which ha e h en planted f ol < ul Sowers for Sorists. 

Azulminsaure,/. azulmic acid, azur, azurblau, azum, a. azure, sky-blue. Azurstein, m. lapis lazuli, azyklisch, a. acyclic. 

Lasur, /. azure azurite glazing, glaze. — m. lapis lazuli. 

Instead of using Methylene Blue, Azure B is reduced and acylated.4 The resulting leucos 8a-t are also described as useful in electrolytic recording.5... 

As in the case of the leucos Azure A and B, the exocyclic acyl group is not eliminated on oxidation, resulting in a Methylene Blue-type cationic... 

Leuco Azure A or B is obtained by refluxing the dye in an acid anhydride in the presence of zinc powder wherein the dye is reduced and acylated at the same time. 

Synthetic Method 1 6-(dimethylamino)-3-(N-acetyl-N-methylamino)-10-acetylphenothiazine 8a (procedure from US. Patent 4,652,643).5 A mixture of 9.0g of 6-(dimethylamino)-3-(methylamino)phenothiazin-5-ium chloride (Azure B), 150.0ml of acetic anhydride, and lO.Og of zinc dust was maintained at reflux temperature for approximately 4 hs. After the reaction mixture was cooled to ambient temperature, it was poured into ice water with stirring and 300ml of toluene was added. After stirring for approximately 30 min the toluene layer was separated and washed twice, once with tap water and once with saturated aqueous sodium chloride solution. The toluene was then distilled off at reduced pressure. The residue which remained was dissolved in ethyl acetate and separated into various components by subjecting the solution to column chromatography using silica gel as substrate. Elution with ethyl acetate yielded a white-colored solid. 

Azure A can be reduced to an air sensitive intermediate 71 and acylated in one step to produce the ballasted leuco 72 which can be isolated and capped with the dye chloroformate 69 to give the ballasted yellow dye release developer 73. 

Lawrence and Ducharme [489] have described a fast, simplified method for the detection of fluorescent whiteners in polymers, in which the polymer dissolution was applied directly to the thin layer. Also the separation of optical brighteners (Leucopur EGM, Azur 4, Azur 5, Hostalux ABC, Uvitex OB, Eastobrite OB) from plastics and migration into water and olive oil was studied by HPTLC on RP-18 silica using various mobile phase mixtures and UV detection [490]. 

The property of polyanions to give metachromatic reactions with basic dyes80 (see Section XI) has been widely exploited for the titration of glycosaminoglycans. Because of its high charge-density, heparin displays large shifts in the visible spectrum of the dye upon complex-formation, and can conveniently be titrated (most commonly, with Methylene Blue or Azure A), even in the presence of minor proportions of other glycosaminoglycans. It should be realized that quantitative responses with metachromatic dyes are different for different pure heparin... 

To investigate heparin release in response to an electric current, the swollen heparin-polymer matrix was attached to a woven platinum cathode in a continuously stirred PBS solution (pH 7.4), and an electric current of 20 mA was applied. When the electric current was on, the polymer surface facing the cathode dissolved, thereby releasing heparin. The amount of heparin released was assayed by the Azure II method at pH 11 to prevent complexation of the two dissolved polymers. The release pattern of heparin showed a complete on-off profile in response to the applied electric field, as shown in Figure 23 [50],... 

Observatoire de la Cote d Azur arecio<3obs-nice. f r, recio0pd.astro.it... 

Cassiopee UMR6202, OCA, Observatoire de Nice-Cote d Azur, France... 

Observatoire de la Cote d Azur, Dpt. Cassiopee, UMR/CNRS 6202, BP4229, 06304 Nice cedex 4, Prance (laverny obs-nice.fr)... 

Wang and Pek [185] have described a simple titration method applicable to the analysis of cationic surfactants in sea water. Methyl orange and azure A were used as primary dye and secondary dye, respectively. The method is free from interference by high levels of inorganic salts in sea water. 

Carbohydrates—periodic acid— Schiff (use ref. 12 controls) Nucleic acids—azure bluea... 

Azure Lead, selenium, CuCI2 (and other copper compounds when moistened with HCI) CuBr2 appears azure blue, then is followed by green. 

To which of the following do the underlined words azure world most likely refer ... 

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