Aziridine Is a Broad-Spectrum Activity-Based Retaining P-Exoglucosidase Probe

Cyclophellitol Aziridine Is a Broad-Spectrum Activity-Based Retaining p-Exoglucosidase Probe 

Insitu Monitoring of Active-Site-Directed GBA Chemical/Pharmacological Chaperones 

Chemical/pharmacological chaperone strategies aim at correcting this impaired folding through stabilization of the enzyme in its proper fold, which can be achieved by inhibition of the enzyme active site. The caveat of this strategy 

Determine GBA activity using fluorogenic subtrate assay 

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