Atropine sulfate diphenoxylate

Likudin M griseofulvin Lofene atropine sulfate, diphenoxylate... [Pg.661]

Jacutin, Kildane, Kwell, Kwildane, Lencid, Locion-V, Lomotil atropine sulfate, diphenoxylate... [Pg.661]

Not more than 2.5 milligrams of diphenoxylate and not less than 25 micrograms of atropine sulfate per dosage unit. [Pg.244]

Oral 1 mg (with 0.025 mg atropine sulfate) tablets Diphenoxylate (generic, Lomotil, others)... [Pg.1513]

Diphenoxylate hydrochloride Tablets with atropine sulfate HPLC Dissolution C-8 methanol (1% ammonium hydroxide) (4 1) Methanol-potassium 210 nm HPLC [3,922] enantiomers [919] USP 23, TLC, BP, p. [5]... [Pg.172]

I. M. Jalal, S. I. Sa sa, A. H. Abusaleh, and H. S. Khalil, Determination of diphenoxylate hydrochloride and atropine sulfate in tablet formulations by reversed-phase HPLC, Anal. Lett., 73(B20) 2551 (1985). [Pg.434]

Diphenoxylate hydrochloride Tablets with atropine sulfate HPLC Dissolution C-8... [Pg.304]

Diphenoxylate Hydrochloride/Atropine Sulfate Brand name Lomotil Class Antidiarrheals... [Pg.22]

Dimethyl Sulfoxide topical solution Diphenoxylate Hydrochloride and Atropine Sulfate oral solution Enflurane... [Pg.477]

Convulex valproic acid, co-phenotrope atropine sulphate diphenoxylate, copper sulphate cupric sulfate, corbadrine levonordefrin. [Pg.83]

Note Diphenoxylate is almost always prescribed with atropine sulfate... [Pg.186]

DIPHENOXYLATE HYDROCHLORIDE WITH ATROPINE SULFATE (Lomotil)... [Pg.206]

Diphenoxylate is a meperidine congener that is approved for the treatment of diarrhea (see Chapter 37). Diphenoxylate hydrochloride is available only in combination with atropine sulfate (LOMOTIL, Others). The recommended daily dosage of diphenoxylate for the treatment of diarrhea in adults is 20 mg in divided doses. Difenoxin (motofen), a metabolite of diphenoxylate, has actions similar to those of the parent compound. [Pg.360]

Kappa receptor activation does not appear to be responsible for dependence, euphoria, or effects on smooth muscle. Increases in cerebral blood flow and (possibly) increased intracranial pressure result from the respiratory depressant actions of opioid analgesics. The latter effects are due to increased arterial PrOj, which results from mu receptor inhibition of the medullary respiratory center. However, the activation of kappa receptors contributes to analgesia at the spinal level and is probably responsible for sedative actions of the opioids. The answer is (D). Codeine and possibly nalbuphine could decrease gastrointestinal peristalsis but not without marked side effects (and a prescription). Dextromethorphan is a cough suppressant. The other two drugs listed are opioids with antidiarrheal actions. Diphenoxylate is not available over-the-counter since it is a constituent of a proprietary combination that includes atropine sulfate (Lomotil). Loperamide is available over-the-counter. The answer is (D). [Pg.286]

Difenoxin, the active metabolite of diphenoxylate (as described above), also is used as an antidiarrheal agent. Tablets contain 1 mg of difenoxin and 0.025 mg of atropine sulfate. Dosage, uses, and effectiveness are similar to those of diphenoxylate. [Pg.1009]

Anti-diarrhea combinations are miscellaneous antidiarrheals that include colistin sulfate, furazolidone, loperamide, lactobadUus, and octreotide acetate. You may know these brand names drags to alleviate diarrhea Lomotil (diphenoxylate HCl with atropine sulfate) and parepectolin (paregoric, kaolin, pectin, alcohol). Most contain a synthetic narcotic ingredient. [Pg.361]

A depressed woman taking daily doses of conjugated oestrogens 1.25 mg and amitriptyline 75 mg, was also given furazolidone 300 mg daily and diphenoxylate with atropine sulfate. Two days later she began to experi-enee blurred vision, profuse perspiration followed by alternate chills and hot flushes, restlessness, motor activity, persecutory delusions, auditory hallueinations and visual illusions. The symptoms cleared within a day of stopping the furazolidone. The reasons are not understood but the authors point out that furazolidone has MAO-inhibitory properties and that the symptoms were similar to those seen when the tricyclic antidepressants and MAOIs interaet. However the MAO-inhibitory activity of furazolidone normally develops over several days. Whether the concurrent use of atropine and amitriptyline (both of which have antimuscarinic activity)... [Pg.1245]

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