Cocaine atropine

Tropane alkaloids Tropane Atropine Cocaine Hyoscyamine Scopolamine/ hyoscine... 

An alkaloid is a complex organic chemical substance found in plants, which characteristically combines nitrogen with other elements, has a bitter taste, and typically has some toxic, stimulant, analgesic effects. There are many different alkaloids, 30 of which are found in the opium plant. While morphine is the most important alkaloid in opium—for its natural narcotic qualities as well as providing the chemical structure for heroin—another alkaloid, codeine, is also sought after for its medicinal attributes. Other alkaloids include papaverine, narcotine, nicotine, atropine, cocaine, and mescaline. While the concentration of morphine in opium varies depending on where and how the plant is cultivated, it typically ranges from 3 percent to 20 percent. 

To disinfect water (well, ponds) for stomach wash in alkaloidal poisoning (except atropine cocaine which are not efficiently oxidized). 

These are the group of alkaloids that possess a 8-methyl-8-aza-hicyclo [l,2,3]octane or tropane skeleton, e.g. atropine, cocaine and scopolamine. Tropane alkaloids occur mainly in plants from the families Solanaceae and Erythroxylaceae. 8-Aza-hicyclo[l,2,3]octane, i.e. tropane without the 8-methyl group, is known as nortropane. 

Tropine alkaloids Atropine, cocaine, eegonine, scopolamine, tropine... 

John et al. added twice the volume of ACN to plasma samples thus generating a supernatant containing 66 % (v/v) ACN. Merely dilution with aqueous HPLC solvent A [0.1 % formic acid (FA)] was necessary prior to injection allowing quantitative analysis of R- and. S -hyoscyaminc [49] as well as atropine, cocaine, homatropine, ipratropium, littorine, iV-buty 1-scopolamine and scopolamine, simultaneously [50], Recoveries were greater than 85 % (Table 2). Despite this crude preparation procedure effects on ionization were negligible. 

S,opium alkaloids, quinine, cinchonine, nicotine,atropine, cocaine Separation on ion-exchange resins (ligand-exchange LC)... 

When one considers the therapeutic impact of morphine, quinine, digitalis, ergot, atropine, cocaine, reserpine, and vincaleukoblastine, to name but a few, it is evident how great is the debt of medicine to plant-derived drugs even today. If one adds the synthetic derivatives and variants of plant-derived products, the role of natural products from plant sources has been most impressive. 

The alkaloids of the tropane group show a series of common chemical characteristics, particularly that of being esters of organic acids combined with bicyclic hydramines. They include Z-hyoscyamine and its isomer atropine, cocaine, scopolamine or hyoscine, and a series of secondary alkaloids. 

Bieganowska and Petruczynik (1994) studied the separation of 15 alkaloids on unmodified silica gel in reversed-phase ion-association systems. Tombesi et al. (1994) purified 15 alkaloids (including atropine, cocaine, codeine, and quinine) by TLC decomposition of their picrates using silica gel and alumina sorbents identification was based on melting points and UV-visible spectra. 

Alkaline, drug like substances found in certain plants. All alkaloids contain nitrogen in a nonprotein form. Some of the important alkaloids used in medicine are atropine, cocaine, morphine, quinine, and strychnine. 

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