Tropane group

Tritopine. See Laudanidine. Tropacocaine, 62, 64, 79, 100 pharmacological action, 106 Tropane, 87, 108 Tropane group alkaloids, 64, 776 pharmacological action, 105 Tropeines, 73, 79, 81 Tropehone, 80 Tropic acid, 72... 

Tropane Group. SolanaceOus Alkaloids, Convolvine and Allied Alkaloids, Dioscorine, Alkaloids of Coca Leaves (Erythroxylon coca). ... 

N. tfibacuTn of nomicotine in N. glutinosa and of anabasine in N. glauca. In the tropane group, i-hyoscyamine predominates in A. belladonna and f-hyoscine in Datura metel L. (68). The distribution of the alkaloids in a graft whose stock and scion produce different kinds may thus prove illuminating. 

Results of some of the grafting experiments described in the previous section sug t strongly that alkaloids, in particular those of the.nicotine and tropane groups, are carried from the root and distributed throughout the aerial parts of the plant. The obvious agent of transport is the transpiration stream, and its participation has been confirmed by Dawson s (82) observations on the sap bleeding from cut stumps of Connecticut tobacco plants. The sap could be seen to exude from the xylem only and contained... 

Duboisia. Interesting observations have been made on the alkaloids of the Duboisias in recent years. Duboisia myoporoides contains alkaloids of the tropane group. It has a wide geographical range in Eastern Australia... 

The alkaloids of the tropane group show a series of common chemical characteristics, particularly that of being esters of organic acids combined with bicyclic hydramines. They include Z-hyoscyamine and its isomer atropine, cocaine, scopolamine or hyoscine, and a series of secondary alkaloids. 

All members of the monosubstituted tropane group are derived from tropine (10), pseudotropine (11), and their norderivatives nortropine (12) and pseudonortropine (13). 

Similar results have been published for other Solanaceae alkaloids, namely, those of the tropane group. Heine (1942) grafted Datura scions upon Nicotiana rustica and found that nicotine accumulated instead of tropane alkaloids. This finding was confirmed by Hills et al, (1946) with Nicotiana-Duboisia grafts. The tobacco scion on Duboisia root was found to accumulate tropane alkaloids. Surprisingly, the tobacco scion accumulated both hyoscine and the unesterified tropine. In all grafts between plants... 

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