Arteriosclerosis Myocardial infarct

In the Soviet Union orotic acid has been studied for a long time in relation to arteriosclerosis, myocardial infarction [449-450] and various cardiopathogenic changes [451-455]. The effect of precursors of nucleic acid synthesis on myocardial contractile function was followed by Zharov and others [456,457]. However, the effect of orotic acid on the development of myocardial hypertrophy was also studied in other countries [458-463]. 

V9 Villanyi, P., Votin, J. and Rahlfs, V. Arteriosclerosis, myocardial infarct and blood lipids their therapeutic modification by magnesium orotate. Wien. Med. Wochenschr., 120, 76-83 (1970) (Germ.)... 

F2. Fager, G., Wiklund, O., Olofsson, S.-O., Wilhelmsen, L., and Bondjers, G., Multivariate analysis of serum apolipoproteins and risk factors in relation to acute myocardial infarction. Arteriosclerosis 1, 273-279 (1981). 

In the western countries the most prevalent form of heart disease is coronary heart disease, i.e. the sequelae of atherosclerosis [18] of the coronary arteries. Culmination of coronary arteriosclerosis is manifested by erratic heart activity, arrhythmia or fibrillation, i.e. in drastic cases by coronary occlusion, myocardial infarction and sudden death. Mortality from coronary heart disease varies greatly from one country to the other. The following statistics represent the death rate due to coronary heart disease among the male population between the ages of... 

Amouyel, P., Isorez, D., Bard, J.M., Goldman, M., Lebel, P., Zylberberg, G., and Fruchart, J. C., 1993. Parental history of early myocardial infarction is associated with decreased levels of lipoparticle AI in adolescents. Arteriosclerosis, Thrombosis, and Vascular Biology. 13 1640-1644. 

Dissection material from patients with various diseases or after death from various causes (myocardial infarction, cerebral arteriosclerosis, neoplasma, leukaemia, strangulation, etc.). 

Maresca G, Diblasio A, Marchioli R et al. Measuring plasma fibrinogen to predict stroke and myocardial infarction An update. Arteriosclerosis Thrombosis and Vascular Biology 1999 19 1368-1377. 

In recent years, studies have indicated that arteriosclerosis may be due to vascular inflammation, and that CRP concentration in the blood correlates with the degree of fimctional disorder of the vascular endothelium High CRP serum levels have been shown to be a risk factor for anginal damage or myocardial infarction-induced stroke - ). Therefore, a highly sensitive and accurate method of measuring CRP is clinically significant. 

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