Arsenic systematic reviews

In a systematic review of the experimental and epidemiological data, Navas-Aden et al. (2006) argue that the evidence to date is inconclusive for a role of arsenic in the development of diabetes mellitus. Pooling the results from the Taiwan and Bangladesh studies, which were from extreme arsenic exposures, there was a risk of 2.5 for the development of diabetes. However, they point out, because of the types of studies conducted, particularly with characterization of the exposures, it was hard to interpret the association. In addition, the occupational studies that they examined showed increased and decreased morbidity from diabetes due to arsenic exposure. The general population studies, which typically had much lower arsenic exposures, were inconclusive. 

Navas-Acien, A., Sharrett, A.R., Silbergeld, E.K. et al. (2005) Arsenic exposure and cardiovascular disease A systematic review of the epidemiologic evidence. American Journal of Epidemiology, 162(11), 1037-49. 

Systematic reviews Arsenic enters human food chain possibly by arsenic accumulations in edible plants and crops, from contaminated soils and irrigation water that further reach livestock meat, animal products like milk and egg [9 ]. However in regions like Latin America, despite its long history of arsenic contamination, are rather poorly reported for arsenic toxicity. A systematic review revealed that at least 4.5 million people in Latin America are chronically exposed to high arsenic levels (>50 ng/L) with increased risks of adverse health effects like internal and external cancers, reproductive toxicity and childhood cognitive deficient function [10 ]. 

Psychological In a systematic review and mete-analysis, the authors found an association of arsenic, cadmium and manganese exposure with neurodevelopment and behavioural disorders in children. Forty-one articles that evaluated the effects of metallic elements on neurodevelopment and behavioural disorders that met the inclusion criteria... 

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