Application of polyester-based biodegradable fibres

Application as scaffolds was suggested also for centrifugally spun fibres. Although almost no cell adhesion was observed for unmodified fibres investigated by SEM, subsequent acid or alkali treatment resulted in a cell-adhesive material which may have a potential value as wound scaffold. 

In fact, most biodegradable polyester-type fibres are intended for medical purposes, although the application is not limited to scaffolds. Poly(caprolactone) gravity spun fibres were found to attach fibroblasts and myoblasts. Due to high fibre compliance and a potential for controlling the fibre surface architecture, the fibres can be recommended to be used as compliance-matched implants for soft tissue engineering.  

Poly(caprolactone) gravity spun fibres were used also as a carrier for ovalbumin or progesterone. The delayed dmg release was observed the rate depends on several factors, e.g. concentration and size of the protein particulates, which enables a programmed delivery of drugs or supporting agents for tissue engineering. 

An industrial application was suggested for copolymers of poly(caprolactone) and poly(ethylene terephthalate) as a material for elastic seat belts. In this case the impact on the passenger was damped by the increased elasticity of the belt, compared to the belt made of pure PET, decreasing the extent of injuries caused by contact with the seat belt.  

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