Apatite-Wollastonite Glass Ceramic

The following bioactive glass-ceramics are used for implants in human medicine CERABONE (apatite-wollastonite glass-ceramic), CERAVITAL (apatites devitrite glass-ceramic), and BIOVERJT I (mica-apatite glass-ceramic). 

Kokubo, T., Shigematsu, M., Nagashima, Y., Tashiro, M., Nakamura, T., Yamamuro, T. and Higashi, S. (1982) Apatite- and wollastonite-containing glass-ceramics for prosthetic application. Bulletin of the Institute for Chemical Research, Kyoto University, 60, 260-268. 

Juhasz, J.A., Best, S.M., Bonfield, W., Kawashita, M., Miyata, N., Kokubo, T. and Nakamura, T. (2003) Apatiteforming ability of glass-ceramic apatite-wollastonite — polyethylene composites effect of filler content Journal of Materials Science-Materials in Medicine, 14, 489-95. 

H. Matsuoka, H. Akiyama, Y. Okada, C. Shigeno, J. Konishi, T. Kokubo, T. Nakamura, In vitro analysis of the stimulation of bone formation by highly bioactive apatite- and wollastonite-containing glass-ceramic Released calcium ions promote osteogenic differentiation in osteoblastic ROS17/2.8 cells, J. Biomed. Mater. Res. 47 (1999) 176-188. 

Nishio, K., Neo, M., Akiyama, H., Okada, Y., Kokubo, T., and Nakamura, T. (2001), Effects of apatite and Wollastonite containing glass-ceramic powder and two types of alumina powder in composites on osteoblastic differentiation of bone marrow cells, /. Biomed. Mater. Res. 55(2) 164-176. 

This crystal growth mechanism is linked to surface nucleation. The success-fill application of the mechanisms of surface nucleation and crystallization in the development of cordierite (Semar and Pannhorst, 1991), apatite-wollastonite (Kokubo 1991), and leucite glass-ceramics (Holand et al., 1995a) has already been mentioned in Section 1.4. 

CERABONE is the most widely and successfiilly used bioactive glass-ceramic for bone replacement in human medicine. Nippon Electrical Glass Co., Ltd. produces the apatite-wollastonite (A-W) glass-ceramic under the brand name of CERABONE A-W. It is distributed as a biomaterial by Lederle Qapan), Ltd. 

Kokubo T, Shigamatsu M., Nagashima Y., Tashiro M., Nakamura T, Yamamuro Y., and Higashi S., "Apatite and Wollastonite-Containing Glass-Ceramics for Prosthetic Application," Bull Inst. Chem. Res., Kyoto Univ., 60, 260-68 (1982). 

Kokubo, T., Ito, S., Shigematsu, M., Sanka, S. Yamamuro, T. (1987) Fatigue and life-time of bioactive glass-ceramic A-W containing apatite and wollastonite. J Mater Sci, 22, 4067-70. 

Ono, K Yamamuro, T Nakamura T Kokubo, T. Apatite-wollastonite containing glass ceramic granule-fibrin mixture as a bone graft filler Use with low granular density. J. Biomed. Mater. Res., 1990. 24. 11-20. 

T. Kokubo, M. Shigematsu, Y. Nagashima, M. Tashiro, T. Nakamura, S. Higashi, Apatite and wollastonite containing glass-ceramics for prosthetic application, BuU. Inst. Chem. Res. 60 (1982) 260-268. 

A supersaturated bioinspired solution was used to coat alumina and zirconia substrates with a thin, poorly crystalline layer of OCP that after heat treatment at 1050 °C for 1 h was converted to hydroxyapatite with particle size of 300 nm (Pribosic, Beranic-Klopcic and Kosmac, 2010). Stefanic et al. (2012) applied a related method to rapidly deposit an OCP layer by a two-step process onto yttria-stabilised tetragonal zirconia polycrystal (Y-TZP). 80vol% Mg-PSZ/20 vol% alumina substrates were used by Nogiwa and Cortes (2006) to deposit biomimetically by immersion in 1.4 SBF a bone-like apatite coating of 15-30 pm thickness, using a bed of either wollastonite ceramics or bioactive glass as an additional source of Ca2+ ions. 

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