Antipsychotic olanzapine

McLellan AT, Kushner H, Metzger D, et al The fifth edition of the Addiction Severity Index. J Subst Abuse Treat 9 199—213, 1992 Mechanic JA, Maynard BT, Holloway FA Treatment with the atypical antipsychotic, olanzapine, prevents the expression of amphetamine-induced place conditioning in the rat. Prog Nemopsychopharmacol Biol Psychiatry 27 43—54, 2003... 

Bymaster F, Calligaro DO, Falcone JF, et al (1996). Radioreceptor binding profile of the atypical antipsychotic olanzapine. Neuropsychopharmacology 14, 87—96. 

Choice of a Mood Stabilizer. With the advance of atypical antipsychotics and an ever-expanding list of anticonvulsants, the number of medications reported to treat acute mania and hypomania continues to grow. In fact, all of the atypical antipsychotics, olanzapine, quetiapine, risperidone, ziprasidone, and aripiprazole have FDA approval for the treatment of acute mania. Long-term protection against future episodes of illness has also been demonstrated with several of these agents, which can influence the choice of initial therapy. 

Antidepressants amitriptyline, clomipramine, imipramine, moclobemide, citalopram Antipsychotics olanzapine... 

Examples of recent work carried out by the DSRU includes the examination of mortality rates and cardiac arrhythmias between sertindole and two other at)q)ical antipsychotics, olanzapine and risperidone. Tolterodine, an agent often used for urinary frequency and bladder instability, is the latest drug to be examined by the DSRU.135... 

PHC431, 2005PHC389) discussions. The specialized review (1993H601) surveyed the synthesis of 1,5-benzodiazepines with three-, four- and five-membered rings fused to different positions of the 1,5-benzodiazepine skeleton. Synthesis of DNA-interactive pyrrole[2,l-c][l,4]benzodiazepines (1994CR433) and medicinal chemistry aspects of the novel thieno benzodiazepine antipsychotic Olanzapine (1997MI1743) have been reviewed. 

Olanzapine. To date, case reports and an open-label case series have described positive responses to the atypical antipsychotic olanzapine in subjects with PDDs. In the case series, six of seven children, adolescents, and adults with autistic disorder and other PDDs (mean age, 20.9 +/— 11.7 years range 5-42 years) who completed the 12-week open-label trial were responders (Potenza et al., 1999). Significant improve-... 

Pilowsky LS, Busatto GF, Taylor M, et al. Dopamine D2 receptor occupancy in vivo by the novel atypical antipsychotic olanzapine-a 123IBZM single photon emission tomography (SPET) study. Psychopharmacology 1996 124 148-153. 

We would emphasize that, while all of these approaches are theoretically important and may possess clinical applicability, with the exception of the atypical antipsychotic olanzapine, none is presently approved by the FDA for treatment of bipolar disorder. 

First-generation antipsychotics Olanzapine, quetiapine, zotepine Clozapine First-generation antipsychotics... 

VALPROATE ANTIPSYCHOTICS -OLANZAPINE Risk of bone marrow toxicity Additive effect Monitor FBC closely warn patients to report sore throat, fever, etc. 

This requires ingenuity of research and marketing alike. Lilly succeeded in several of the U.S. states—most of which pay for this chronic drug treatment—to make, according to the New York Times, the antipsychotic olanzapine the single largest line item in the budget. 

Leucht S, Pitschel-Walz G, Abraham D, Kissling W. Efficacy and extrapyramidal side-effects of the new antipsychotics olanzapine, quetiapine, risperidone, and sertin-dole compared to conventional antipsychotics and placebo. A meta-analysis of randomized controlled trials. Schizophr Res 1999 35(l) 51-68. 

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