Addiction Severity

McLellan AT, Kushner H, Metzger D, et al The fifth edition of the Addiction Severity Index. J Subst Abuse Treat 9 199—213, 1992 Mechanic JA, Maynard BT, Holloway FA Treatment with the atypical antipsychotic, olanzapine, prevents the expression of amphetamine-induced place conditioning in the rat. Prog Nemopsychopharmacol Biol Psychiatry 27 43—54, 2003... 

Some of these measures are part of larger, semistructured interviews administered by the therapist. The most commonly used assessments in this category are a family of instruments developed mainly in the Veterans Administration (VA) hospital system. The first instrument in this family is known as the Addiction Severity Index (ASI McLellan et al., 1985). The ASI assesses for a wide variety of biographical data, so it has the advantage of potentially being used as part of an intake interview. The ASI asks about consequences in a wide variety of life domains, and determines recent and lifetime patterns of drug and alcohol use. The ASI also detects recent and lifetime occurrence of problems in these different life domains (e.g., work). Each domain can be scored for the severity of the problems based upon the responses of the client and the clinical judgment of the interviewer. The ASI can be administered by computer to provide for rapid interpretation of answers. 

Kaminer, Y., Bukstein, O., Tarter, R. (1989). Teen Addiction Severity Index (T-ASI) Clinical and research implications A preliminary report. National Institute on Drug Abuse Research Monograph, 95, 363. 

Meyers, K., McLellan, A. T., Jaeger, J. L., Petdnati, H. M. (1995). The development of the Comprehensive Addiction Severity Index for Adolescents (CASI-A) An interview for assessing multiple problems of adolescents. Journal of Substance Abuse Treatment, 12, 181-193. 

Janis, L. and Mann, C. (1977) Decision making, New York Free Press. McLellan, A.T., Luborsky, L., Cacciola, J., Griffith, J., Evans, F., Barr, H., and O Brien, C.P, (1985) New data from the Addiction Severity Index , Journal of Nervous and Mental Disease, 173 412-23. 

Methadone (Dolophine) Full morphine-like actions, weaker sedative. Detoxification of narcotic addiction. Severe pain in hospitalized patients. Similar to morphine. 

McLellan, A. T., Luborsky, L., Cacdola, J., (jriffith, J. McGaham, P, and O Brien, C. P. (1986) Guide to the Addiction Severity Index Background, Administration, and Field Testing Results, National Institute on Drag Abuse, Treatment Research Reports, Rockville, MD. 

Maternal depressive symptoms are associated with neurodevelopmental patterns of reduced arousal and increased stress. Among 13 808 screened subjects from Honolulu, 1632 were eligible and 176 mothers were enrolled prenatal metamfetamine exposure combined with maternal depression was not associated with any additional neurodevelopmental differences [35 ]. When adjusted for co-variates, metamfetamine exposure was associated with lower arousal and higher lethargy scores. Only 136 biological mothers with child custody (50 of whom had used metamfetamine) had the Addiction Severity Index (ASI) administered at 1 month. The NICU Network Neurobehavioral Scale (NNNS) was administered to the neonate within the first 5 days of fife by an examiner blinded to metamfetamine exposure. There were several limitations to this study. The severity of depression in the mothers was assessed not at the neonatal visit but after 1 month. Since only the biological mothers were included in the study, the sample size was limited, because several infants who had been exposed to metamfetamine were placed in foster care or the care of relatives, so that data from their biological mothers was not assessed. 

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