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Antiparkinsonism Agents

CENTRALLY ACTING MUSCLE RELAXANTS AND ANTIPARKINSONISM AGENTS 15... [Pg.1]

Iminodihydropyridazine derivatives of type (39) have been claimed recently as antiparkinsonism agents [123],... [Pg.16]

Newman-Tancredi, A., Cussac, D., Quentric, Y., Touzard, M., Verriele, L., Carpentier, N. and Millan, M.J. (2002) Differential actions of antiparkinson agents at multiple classes of monoaminergic receptor. III. Agonist and antagonist properties at serotonin, 5-HT... [Pg.152]

CNS When used to treat extrapyramidal reactions resulting from phenothiazines in psychiatric patients, antiparkinson agents may exacerbate mental symptoms and precipitate a toxic psychosis. [Pg.1300]

Drugs that may interact with anticholinergic antiparkinson agents include... [Pg.1300]

Mechanism of Action An antiparkinson agent that inhibits the enzyme, catechobO-methyltransferase (COMT), potentiating dopamine activity and increasing the duration of action of levodopa. Therapeutic Effect Decreases signs and symptoms of Parkinson s disease. [Pg.431]

Topiramate, another antiepileptic drug, may also be helpful in a dose of 400 mg daily, built up gradually. Small quantities of alcohol may suppress essential tremor but only for a short time. Alprazolam (in doses up to 3 mg daily) or gabapentin (100-2400 mg/d) is helpful in some patients. Others are helped by intramuscular injections of botulinum toxin. Thalamic stimulation by an implanted electrode and stimulator is often worthwhile in advanced cases refractory to pharmacotherapy. Diazepam, chlordiazepoxide, mephenesin, and antiparkinsonism agents have been advocated in the past but are generally worthless. Anecdotal reports of benefit from mirtazapine were not confirmed in a double-blind study, which found no effect on the tremor in most patients. [Pg.614]

Secondly ergot derivatives which reveal a clearcut agonistic activity on prolactin secretion and as antiparkinson agents (20) were inactive on the cyclase. Surprisingly, lisuride and lergotrile were found to be weak antagonists of dopamine stimulated cAMP accumulation, but they could also antagonize the cAMP production stimulated by isoproterenol as... [Pg.27]

Several of the compound types in this chapter have useful biological activities. This is not unexpected since many of those compounds which are effective in the modification of responses to bioamines are themselves organic bases. Quinelorane (114) which is a potent dopamine (D2) agonist has been patented as an antihypertensive and antiparkinsonism agent <85USP4501890>. [Pg.944]

If antiparkinson agents are being used, they should be continued for a few weeks after chlorpromazine is discontinued... [Pg.59]

See other pages where Antiparkinsonism Agents is mentioned: [Pg.297]    [Pg.440]    [Pg.491]    [Pg.153]    [Pg.459]    [Pg.997]    [Pg.1105]    [Pg.150]    [Pg.402]    [Pg.130]    [Pg.124]    [Pg.140]    [Pg.58]    [Pg.650]    [Pg.117]    [Pg.379]    [Pg.455]    [Pg.125]    [Pg.126]    [Pg.1228]   
See also in sourсe #XX -- [ Pg.417 , Pg.420 , Pg.425 , Pg.549 , Pg.553 ]



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