Antidotes Russian

In different years, Russian toxicologists implemented into practice antidotic agents for medical aid to those affected with high toxic... 

TMB-4 (EA 1814), [CisHig C lB, exists as odorless, light tan crystals with a molecular weight- of 446.21 and a melting point of 238-241°C and is also available as the chloride.7 3 Russian and Yugoslavian investigators have reported the use of TMB-4 as an antidote in anticholinesterase poisoning.17 73... 

During the same period, Soviet scientists developed the so-called Russian VX (VR, RVX, R 033) (Kassa et al., 2006 Kuca et al., 2006). The chemical structure of VX was unknown for a long time. Therefore some attempts to resolve this question have been made (Bajgar, 1968). Because of these ambiguities and difficulties in synthesis, model V agent [EDMM, G-ethyl 5-(2-dimethylaminoethyl) methylphosphonothioate] was initially used in the Eastern Block to study antidotal treatment. Another structural analog of VX known as Chinese VX (CVX) was also developed and studied (Eckert et al., 2006). 

Germanchuk, V.G., Zabrodskii, P.F. (2005). Effects of antidotal therapy on development of immunodeficient conditions after acute intoxications with warfare agents and their destruction products. Vestnik Rossiiskoi Medicinskoi Akademii [Bulletin of Russian Medical Academy] 1(4) 234. (In Russian)... 

Klimova, L.K. 1958. Pharmacology of a new Unithiol antidote [in Russian]. Farmakol. Toksikol. (Moscow) 21 53-59. 

In different years, Russian toxicologists implemented into practice antidotic agents for medical aid to those affected with high toxic organophosphorus poisonous substance (PS), such as aphin, dipiroxime, budaxim. The studies have been completed on development and implementation into industrial production of an antidote for self-care and mutual aid, pelixime, as well as a ChR, carboxime (l-4-methyl-5-[21-(benzyl dimethyl ammonium) ethyl]) carbamoilpyridinium-2-aldoxime dichloride [88, 89],... 

Petrov AN, Sofronov GA, Nechiporenko SP et al. (2004). Organophosphorus poison antidotes (in Russian). Ross Khim Zhur (Russ JChem), 48,110— 116. 

The gas used was stated by the Russian Health Minister to be a derivative of fentanyl, an opiate chemical related to morphine,59 perhaps mixed with other agents (Van Damme, 2002). Reports suggesting that atropine, an antidote to anticholinergic nerve agents, did not reverse the effects of the gas whereas naloxone, an antidote... 

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