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Antibiotics inhibitors

Tipper D.J. (1988) Antibiotic Inhibitors cf Bacterial Cell Wall Biosynthesis, 2nd edn. Oxford Pergamon Press. [Pg.180]

Urease assay. When Proteus mirabilis grows in a urea-containing medium it hydrolyses the urea to ammonia and consequently raises the pH of the medium. This production of urease is inhibited by aminoglycoside antibiotics (inhibitors of protein synthesis Chapter 8). In practice, it is difficult to obtain reliable results by this method. [Pg.481]

KE Price, Z Zolli, Jr, JC Atkinson, HG Luther. Antibiotic inhibitors. I. The effect of certain milk constituents. Antibiot Chemother 7 672-688, 1957. [Pg.74]

Drugs that may affect duloxetine include inhibitors of CYP1A2 (eg, fluvoxamine, guinolone antibiotics), inhibitors of CYP2D6 (eg, fluoxetine, guinidine, paroxetine), and alcohol. [Pg.1073]

Poison(s). See also Insecticides, Antibiotics, Inhibitors cyanide 590 hydroxylamine 590 Polar membrane 5 Polar molecules 50 definition of 48 hydration of 50 Polarizability 590... [Pg.928]

The second stage of cell wall synthesis. An ATP-requiring amidation of glutamic acid that occurs between steps 2 and 3 has been omitted. Points of action of the antibiotic inhibitors bacitracin and vancomycin are indicated. [Pg.373]

A great many antibiotic inhibitors of ribosome function belong to the class known as aminoglycoside antibiotics. Of these, streptomycin is the best known and the best investigated. Streptomycin binding produces a variety of... [Pg.756]

The structures of some antibiotic inhibitors of protein synthesis. All of the inhibitors shown function by binding to specific sites on the ribosome. [Pg.756]

Clough B, Rangachari K, Strath M, Preiser PR, Wilson RJM (1999) Antibiotic Inhibitors of Organellar Protein Synthesis of Plasmodium falciparum. Protist 150 189... [Pg.419]

L-Digitoxose (53L) and its 4-(9-acetyl derivative are present in a tetrasaccha-ride glycosidically linked in tetrocarcin A, an antibiotic inhibitor of the anti-poptotic Bcl-2 protein family.123 Other tetrocarcins have been isolated from the culture of Micromonospora chalcea KY 11091.124 From another strain of Micromonospora, analogues of tetrocarcin A, called arisostatins A and B, containing isobutanoyldigitoxose instead of acetyldigitoxose were isolated.125... [Pg.167]

Current commercial inhibitors of /3-lactamases include clavulanic acid (an oxapenam see Table 1), sulbactam, and tazobactam (two penam sulfones see Table 1). They are effective only against the class A serine /3-lactamases and they are administrated in the form of antibiotic/inhibitor combinations <2006BP930> Augmentin (amoxicillin/clavulanic acid), Timentin (ticarcillin/clavulanic acid), Unasyn (ampicillin/Sulbactam), Zosyn (piperacillin/tazobactam). [Pg.224]

Little work has been done on the effect of anabolic inhibitors on cellular heat dissipation probably because there is empirical evidence that anabolic processes do not contribute significantly to it (see p. 312). Loike et al. (1981) found that 0.07 mmol dm-3 cycloheximide, an antibiotic inhibitor of protein synthesis, had no effect in 30 minutes on the heat production of murine macrophages. On the other hand, Krakauer and Krakauer (1976) showed that long-term exposure of lymphocytes from immunized horses to 1 mg dm-3 cycloheximide considerably reduced heat production. This was likely to be due to a secondary effect of the antibiotic arresting catabolism by inhibiting the turnover of short half-life enzymes. [Pg.317]

The three antibiotic inhibitors of translation that will be used in this experiment are chloramphenicol, cycloheximide, and puromycin (Fig. 23-10). Chloramphenicol is specific for prokaryotic ribosomes, blocking the transfer of the peptide on the tRNA at the P site to the amino acid linked to the tRNA at the A site (the peptidyl transfer reaction). Since the source of the ribosomes used in this experiment is wheat germ (eukaryotic), we would predict that chloramphenicol would not have a great effect on translation. The mechanism of cycloheximide-mediated inhibition is the same as that described above for chloramphenicol, except for the fact that it is specific for the 80S eukaryotic ribosome. Puromycin is a more broad translational inhibitor, effective on both eukaryotic and prokaryotic ribosomes. It acts as a substrate analog of aminoacyl tRNA. When it binds at the A site of the ribosome, it induces premature termination of translation (Fig. [Pg.377]

Antibiotic inhibitors of transcription Section 28,1.9 Burkitt lymphoma and B-cell leukemia Section 28,2.6... [Pg.20]

Weisbium B, Davies J, Antibiotic inhibitors of the bacterial ribosome, Bacteriol Rev, 1968,32(4) 493-528. [Pg.289]

Use Medicine (antibiotic). Inhibitor of lethal yellowing in coconut palm trees feed additive the hydrochloride is TM Terramycin [Pfizer],... [Pg.938]

The spheres removed from SMPs do not support ATP synthesis but do hydrolyze ATP to ADP and phosphate. Thus, ATP synthesis is carried out by Fq/Fi—ATPase (ATP synthase). The subscript o in Fq indicates that it contains the site at which a potent antibiotic inhibitor, oligomycin, binds and inhibits oxidative phosphorylation. Oligomycin does not bind Fi-ATPase and does not inhibit ATP hydrolysis to ADP and phosphate. [Pg.251]

Antibiotics inhibitors of Bacteriai Ceii Waii Biosynthesis... [Pg.1585]

Match the functions in the right column with the antibiotic inhibitors of E. colt transcription in the left column. [Pg.505]

Fig. 26.1.2. Structure of peptidyl nucleoside antibiotic inhibitors of chitin synthesis. Fig. 26.1.2. Structure of peptidyl nucleoside antibiotic inhibitors of chitin synthesis.
Ward, J. B. In Antibiotic Inhibitors of Bacterial Cell Wall Biosynthesis Tipper, D. J. Ed Pergamon Press 1987, p.1-43. [Pg.50]

This reaction was first reported by Angeli in 1896. It is the preparation of hydroxamlc acids from aidehyde and benzosulfohydroxamic acid. As an important class of reagents, hydroxamic acids have found a variety type of applications in inorganic, organic and pharmaceutical chemistry, including antibiotics, inhibitors, and strong metal ion-chelators, etc. As of today, many other methods have been developed to prepare different hydroxamic acids... [Pg.83]

C12H17NO3 M 223.271 Isol. from Cephalosporium caerulens. Antifungal antibiotic. Inhibitor of the biosynth. of fatty acids and steroids. Needles (CCI4 or C6H6). Mp 93 . Bp 000001 120 . [a] 6 +63 (c, 2 in MeOH). [Pg.586]


See other pages where Antibiotics inhibitors is mentioned: [Pg.7]    [Pg.336]    [Pg.111]    [Pg.18]    [Pg.469]    [Pg.1165]    [Pg.1237]    [Pg.583]    [Pg.584]    [Pg.884]    [Pg.1128]    [Pg.456]    [Pg.674]    [Pg.488]    [Pg.1203]    [Pg.309]    [Pg.1623]    [Pg.178]    [Pg.126]   


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