Antacids neutralizing properties

In addition to their acid-neutralizing properties, antacids containing aluminum appear to have properties that can protect the gastric mucosa from peptic injury. These antacids have been shown to protect the mucosa against NSAID- or ethanol-induced injury by a mechanism that involves the production of NO, which promotes mucosal blood flow (Konturek et al 1992). 

Mechanism of Action An antacid that reduces gastric acid by binding with phosphate in the intestine, and then is excreted as aluminum carbonate in feces. Aluminum carbonate may increase the absorption of calcium due to decreased serum phosphate levels. The drug also has astringent and adsorbent properties. Therapeutic Effect Neutralizes or increases gastric pH reduces phosphates in urine, preventing formation of phosphate urinary stones reduces serum phosphate levels decreases fluidity of stools. 

As a dipolar solvent, acetamide finds many uses as a solvent for both inorganic and organic compounds. The solvency has led to widespread uses in industry including applications in cryoscopy, soldering, and the textile industry. The neutral and amphoteric characteristics allow its use as an antacid in the lacquer, explosives, and cosmetics industries. Its hygroscopic properties make it useful as a plasticizer in coatings, fixtures, cloth, and leather, and as a hum-ectant for paper. It is also a raw material in organic synthesis of methylamine and thioacetamide and as an intermediate in preparation of medicines, insecticides, and plastics. 

Heartburn or stomach discomfort is caused by excess hydrochloric acid in the stomach. Hydrochloric acid helps break down the food you eat, but too much of it can irritate your stomach or digestive tract. An antacid product, often made from the base magnesium hydroxide, Mg(OH)2, neutralizes the excess acid. Neutralization (new truh luh ZAY shun) is the reaction of an acid with a base. It is called this because the properties of both the acid and base are diminished, or neutralized. In most cases, the reaction produces a water and a salt. Figure 20 illustrates the relative amounts of hydronium and hydroxide ions between pH 0 and pH 14. 

An acid-base reaction is what you need. You know that bases react with acids to diminish, or neutralize, their properties. In this case, the property of interest is the irritating action of too much acid on your stomach lining. The bases that compose commercial products used to treat acid stomachs are called anti-acids—antacids for short— just for this reason. 

It is a chemical property of an antacid that it can neutralize (eliminate) stomach acid. 

Nanoclays can be categorized into cationic and anionic types. Cationic nanoclays are based on smectite clays. An example is montmorillonite (MMT), a hydrated Al, Mg silicate that may contain cations such as Na+ and Ca++ between the anionic layers. In contrast, anionic clays contain cationic layers and anions such as Cr and in the interlayer space. Typical examples include layered double hydroxides (LDH) and hydrotalcite (HT), a mostly synthetic hydrated magnesium and aluminum carbonate salt. Whereas MMT is commonly used as a nanofiller to improve thermal, mechanical, and barrier properties, LDHs have many attractive properties that lead to application as surfactant adsorbents, biohybrid materials, antacid food formulations, acid neutralizers, and active pharmaceutical ingredients excipients [37, 13, 28, 14, 35]. 

---