Metronidazole Antacids

Drugs that might affect amprenavir include abacavir, aldesleukin, antacids, anticonvulsants, azole antifungals, clarithromycin, cyclosporine, dexamethasone, buffered didanosine, disulfiram, ethanol, indinavir, methadone, metronidazole, nelfinavir, nonnucleoside reverse transcriptase inhibitors, oral contraceptives, rifamycins, ritonavir, saquinavir, St. John s wort, tacrolimus, and zidovudine. 

Drugs that may interact with zalcitabine include antacids, chloramphenicol, cisplatin, dapsone, didanosine, disulfiram, ethionamide, glutethimide, gold, hydralazine, iodoquinol, isoniazid, metronidazole, nitrofurantoin, phenytoin, ribavirin, vincristine, cimetidine, metoclopramide, amphotericin, aminoglycosides, foscarnet, antiretroviral nucleoside analogs, pentamidine, and probenecid. 

Absorption from the gastrointestinal tract can be affected by other drugs and by food. Aluminum, calcium, and magnesium ions in antacids or dairy products form insoluble chelates with all tetracyclines and inhibit their absorption. Food inhibits tetracycline absorption but enhances doxycycline absorption food delays but does not diminish metronidazole absorption fatty food enhances griseofulvin absorption. 

Fosamprenavir PI2 1400 mg bid or 700 mg bid with ritonavir 100 bid or 1400 mg daily with ritonavir 100-200 mg daily. Adjust dose in hepatic insufficiency Separate dosing from antacids by 2 h. Avoid concurrent high-fat meals Diarrhea, nausea, vomiting, hypertriglyceridemia, rash, headache, perioral paresthesias, t liver enzymes See footnote 4 for contraindicated medications. Do not administer with lopinavir/ritonavir or in severe hepatic insufficiency. Also avoid cimetidine, disulfiram, metronidazole, vitamin E, ritonavir oral solution, and alcohol when using the oral solution... 

The coadministration of mycophenolate mofetil with antacids results in decreased absorption. The plasma MPA concentration is significantly reduced by cholestyramine due to binding of the cholestyramine to MPAG in the intestine and interfering with the enterohepatic recirculation of the drug. The bioavailability of mycophenolate mofetil is higher when administered with tacrolimus as opposed to cyclosporine. The bioavailability of MPA is reduced by antibiotics including fluoroquinolones and metronidazole. 

Inhibition of enteral coumarin absorption by adsorbents, e.g., antacids, medicinal charcoal Inhibition of hepatic coumarin metabolism, e.g., by cimetidine, metronidazole ... 

Clinically important, potentially hazardous interactions with antacids, azathioprine, basiliximab, cholestyramine, corticosteroids, cyclophosphamide, cyclosporine, daclizumab, hemophilus B vaccine, mercaptopurine, metronidazole, norfloxacin, tacrolimus, vaccines... 

Amoxicillin, clarithromycin, tetracycline, and metronidazoie have been used in various regimens for H. fy/on-associated GI ulcers, together with H2 blockers, proton pump inhibitors, and antacids e.g., "BMI" regimen bismuth, metronidazole, and tetracycline. 

This macrolide can be used effectively for the treatment of nongonococcal genital infections [331, 332]. In the therapy of H. py/on-associated peptic ulcer disease, combination therapy of spiramycin, metronidazole, and antacid/bismuth resulted in ulcer healing rates of 89-91% and bacteriological eradication rates of... 

The absorption of metronidazole is unaffected by kaolin-pectin, but it is slightly reduced by an aluminium hydroxide antacid and colestyramine, although not to a clinically relevant extent. 

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