Animal studies blood-brain barrier function

Animal studies have shown that carnosine can affect neurological function, not surprising given that fact the dipeptide is synthesized by the brain and that specific transporters for it are present in the choroid plexus (Teuscher et al., 2004), part of the blood-brain barrier. One possible role for carnosine within the neuronal system is modulation in glutamatergic sensory neurons (Bonfanti et al., 1999). For a detailed discussion of carno-sine s function within the mammalian brain, the reader is referred to the fine review by Bonfanti et al. (1999). 

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