Anhydrides with organometallic

Treatment of N hydroxysuccinimide with trifluoroacetic anhydnde gives N trifluoroacetoxysuccinimide quantitatively [27] Some otherwise hardly accessible trifluoroacetylated tertiary alcohols are readily prepared, though in poor yields, by reacting the appropriate anhydride with an excess of an organometallic reagent [22] (equation 11)... 

Furthermore reactions with difluorophosphoric anhydride are of some importance (55). The easy cleavage of the P—0—P-bridge in reactions with organometallic oxides (17) and halides (18) leads to derivatives of difluorophosphoric acid in a very mild way ... 

Torrence P (2002) Carbonylations synthesis of acetic acid and acetic acid anhydride from methanol. In Cornils B, Herrmann WA (eds) Applied homogeneous catalysis with organometallic compounds, vol 1, 2nd edn. Wiley, Weinheim, p 104... 

The Conversion of Anhydrides, Carboxylic Esters, or Amides to Ketones with Organometallic Compounds1659 Alkyl-de-acyloxy-substitution... 

Many examples of the formation of new six-membered rings containing a nitrogen atom in the reaction of isatoic anhydrides with ketones, diketones, various ether derivatives, lactones, and organometallic compounds are known. Thus, the anhydrides 2 and 34 condense with acetophenones and co-methoxyacetophenones in the presence of lithium diisopropylamide at low temperatures with the formation of derivatives of quinolone 35 [17, 18],... 

Avey, A. Schut, D.M. Weakley, T.J.R. Tyler, D.R. (1993) A new water-soluble phosphine for use in aqueous organometallic systems - products from the reactions of 2,3-bis(diphenylphosphino)maleic anhydride with water and oxygen, Inorg. Chem., 52,233-6. 

Diphenylphosphinic mixed anhydrides have been utilized to form peptide bonds. Peptides are easier to isolate by this method than by employing 1,3-Dicyclohexylcarbodiimide. These anhydrides are the method of choice for the formation of amides of 2-alkenoic acids (eq 1 ). Carbodiimide and acyl carbonate methods proved to be inferior. Primary amines result in better yields than secondary amines. This activation protocol can be employed to form thiol esters (eq 2) p-Amino acids are readily converted to p-lactams with chlorodiphenylphosphine oxide (eq 3). Secondary amines work best. This activation protocol has been utilized to convert acids to amines via a Curtius rearrangement. Phenols have been generated from diene acids, presumably via base-induced elimination of diphenylphosphinic acid from the mixed anhydrides to form ketenes which spontaneously cyclize. Acids have been converted to ketones via activation followed by reaction with organometallic reagents (eq 4)."... 

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